Wray GA - Search Results

1

Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection.

Shibata Y, Sheffield NC, Fedrigo O, Babbitt CC, Wortham M, Tewari AK, London D, Song L, Lee BK, Iyer VR, Parker SC, Margulies EH, Wray GA, Furey TS, Crawford GE. Shibata Y, et al. Among authors: wray ga. PLoS Genet. 2012 Jun;8(6):e1002789. doi: 10.1371/journal.pgen.1002789. Epub 2012 Jun 28. PLoS Genet. 2012. PMID: 22761590 Free PMC article.

2

The effects of selection against spurious transcription factor binding sites.

Hahn MW, Stajich JE, Wray GA. Hahn MW, et al. Among authors: wray ga. Mol Biol Evol. 2003 Jun;20(6):901-6. doi: 10.1093/molbev/msg096. Epub 2003 Apr 25. Mol Biol Evol. 2003. PMID: 12716998

3

Positive selection on a human-specific transcription factor binding site regulating IL4 expression.

Rockman MV, Hahn MW, Soranzo N, Goldstein DB, Wray GA. Rockman MV, et al. Among authors: wray ga. Curr Biol. 2003 Dec 2;13(23):2118-23. doi: 10.1016/j.cub.2003.11.025. Curr Biol. 2003. PMID: 14654003 Free article.

4

Transcriptional regulation and the evolution of development.

Wray GA. Wray GA. Int J Dev Biol. 2003;47(7-8):675-84. Int J Dev Biol. 2003. PMID: 14756343 Review.

5

Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans.

Hahn MW, Rockman MV, Soranzo N, Goldstein DB, Wray GA. Hahn MW, et al. Among authors: wray ga. Genetics. 2004 Jun;167(2):867-77. doi: 10.1534/genetics.103.025726. Genetics. 2004. PMID: 15238535 Free PMC article.

6

Positive selection on MMP3 regulation has shaped heart disease risk.

Rockman MV, Hahn MW, Soranzo N, Loisel DA, Goldstein DB, Wray GA. Rockman MV, et al. Among authors: wray ga. Curr Biol. 2004 Sep 7;14(17):1531-9. doi: 10.1016/j.cub.2004.08.051. Curr Biol. 2004. PMID: 15341739 Free article.

7

Ancient and recent positive selection transformed opioid cis-regulation in humans.

Rockman MV, Hahn MW, Soranzo N, Zimprich F, Goldstein DB, Wray GA. Rockman MV, et al. Among authors: wray ga. PLoS Biol. 2005 Dec;3(12):e387. doi: 10.1371/journal.pbio.0030387. PLoS Biol. 2005. PMID: 16274263 Free PMC article.

8

Convergent adaptation of human lactase persistence in Africa and Europe.

Tishkoff SA, Reed FA, Ranciaro A, Voight BF, Babbitt CC, Silverman JS, Powell K, Mortensen HM, Hirbo JB, Osman M, Ibrahim M, Omar SA, Lema G, Nyambo TB, Ghori J, Bumpstead S, Pritchard JK, Wray GA, Deloukas P. Tishkoff SA, et al. Among authors: wray ga. Nat Genet. 2007 Jan;39(1):31-40. doi: 10.1038/ng1946. Epub 2006 Dec 10. Nat Genet. 2007. PMID: 17159977 Free PMC article.

9

The evolutionary significance of cis-regulatory mutations.

Wray GA. Wray GA. Nat Rev Genet. 2007 Mar;8(3):206-16. doi: 10.1038/nrg2063. Nat Rev Genet. 2007. PMID: 17304246 Review.

10

Promoter regions of many neural- and nutrition-related genes have experienced positive selection during human evolution.

Haygood R, Fedrigo O, Hanson B, Yokoyama KD, Wray GA. Haygood R, et al. Among authors: wray ga. Nat Genet. 2007 Sep;39(9):1140-4. doi: 10.1038/ng2104. Epub 2007 Aug 12. Nat Genet. 2007. PMID: 17694055 Free article.

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