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Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial.
Goossens GH, Moors CC, van der Zijl NJ, Venteclef N, Alili R, Jocken JW, Essers Y, Cleutjens JP, Clément K, Diamant M, Blaak EE. Goossens GH, et al. Among authors: cleutjens jp. PLoS One. 2012;7(6):e39930. doi: 10.1371/journal.pone.0039930. Epub 2012 Jun 29. PLoS One. 2012. PMID: 22768174 Free PMC article. Clinical Trial.
Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation.
Goossens GH, Bizzarri A, Venteclef N, Essers Y, Cleutjens JP, Konings E, Jocken JW, Cajlakovic M, Ribitsch V, Clément K, Blaak EE. Goossens GH, et al. Among authors: cleutjens jp. Circulation. 2011 Jul 5;124(1):67-76. doi: 10.1161/CIRCULATIONAHA.111.027813. Epub 2011 Jun 13. Circulation. 2011. PMID: 21670228
Diet-induced weight loss decreases adipose tissue oxygen tension with parallel changes in adipose tissue phenotype and insulin sensitivity in overweight humans.
Vink RG, Roumans NJ, Čajlaković M, Cleutjens JPM, Boekschoten MV, Fazelzadeh P, Vogel MAA, Blaak EE, Mariman EC, van Baak MA, Goossens GH. Vink RG, et al. Int J Obes (Lond). 2017 May;41(5):722-728. doi: 10.1038/ijo.2017.38. Epub 2017 Feb 9. Int J Obes (Lond). 2017. PMID: 28179648 Clinical Trial.
136 results