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Use of ATP analogs to inhibit HIV-1 transcription.
Narayanan A, Sampey G, Van Duyne R, Guendel I, Kehn-Hall K, Roman J, Currer R, Galons H, Oumata N, Joseph B, Meijer L, Caputi M, Nekhai S, Kashanchi F. Narayanan A, et al. Among authors: joseph b. Virology. 2012 Oct 10;432(1):219-31. doi: 10.1016/j.virol.2012.06.007. Epub 2012 Jul 6. Virology. 2012. PMID: 22771113 Free PMC article.
Targeting low molecular weight cyclin E (LMW-E) in breast cancer.
Nanos-Webb A, Jabbour NA, Multani AS, Wingate H, Oumata N, Galons H, Joseph B, Meijer L, Hunt KK, Keyomarsi K. Nanos-Webb A, et al. Among authors: joseph b. Breast Cancer Res Treat. 2012 Apr;132(2):575-88. doi: 10.1007/s10549-011-1638-4. Epub 2011 Jun 22. Breast Cancer Res Treat. 2012. PMID: 21695458 Free PMC article.
Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex.
Echalier A, Bettayeb K, Ferandin Y, Lozach O, Clément M, Valette A, Liger F, Marquet B, Morris JC, Endicott JA, Joseph B, Meijer L. Echalier A, et al. Among authors: joseph b. J Med Chem. 2008 Feb 28;51(4):737-51. doi: 10.1021/jm700940h. Epub 2008 Jan 31. J Med Chem. 2008. PMID: 18232649
Meriolins display potent inhibitory activities toward cyclin-dependent kinases (CDKs) and, to a lesser extent, other kinases (GSK-3, DYRK1A). The crystal structures of 1e (meriolin 5) and variolin B (Bettayeb, K.; Tirado, O. M.; Marionneau-Lambert, S.; Ferandin, Y.; Lozach …
Meriolins display potent inhibitory activities toward cyclin-dependent kinases (CDKs) and, to a lesser extent, other kinases (GSK-3, DYRK1A) …
Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases.
Bettayeb K, Tirado OM, Marionneau-Lambot S, Ferandin Y, Lozach O, Morris JC, Mateo-Lozano S, Drueckes P, Schächtele C, Kubbutat MH, Liger F, Marquet B, Joseph B, Echalier A, Endicott JA, Notario V, Meijer L. Bettayeb K, et al. Among authors: joseph b. Cancer Res. 2007 Sep 1;67(17):8325-34. doi: 10.1158/0008-5472.CAN-07-1826. Cancer Res. 2007. PMID: 17804748
Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis.
Jarry M, Lecointre C, Malleval C, Desrues L, Schouft MT, Lejoncour V, Liger F, Lyvinec G, Joseph B, Loaëc N, Meijer L, Honnorat J, Gandolfo P, Castel H. Jarry M, et al. Among authors: joseph b. Neuro Oncol. 2014 Nov;16(11):1484-98. doi: 10.1093/neuonc/nou102. Epub 2014 Jun 2. Neuro Oncol. 2014. PMID: 24891448 Free PMC article.
1,478 results