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LEDGF (p75) promotes DNA-end resection and homologous recombination.
Daugaard M, Baude A, Fugger K, Povlsen LK, Beck H, Sørensen CS, Petersen NH, Sorensen PH, Lukas C, Bartek J, Lukas J, Rohde M, Jäättelä M. Daugaard M, et al. Among authors: rohde m. Nat Struct Mol Biol. 2012 Aug;19(8):803-10. doi: 10.1038/nsmb.2314. Epub 2012 Jul 8. Nat Struct Mol Biol. 2012. PMID: 22773103
Hsp70-2 is required for tumor cell growth and survival.
Daugaard M, Jäättelä M, Rohde M. Daugaard M, et al. Among authors: rohde m. Cell Cycle. 2005 Jul;4(7):877-80. doi: 10.4161/cc.4.7.1838. Epub 2005 Jul 11. Cell Cycle. 2005. PMID: 15970673
Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.
Petersen NH, Olsen OD, Groth-Pedersen L, Ellegaard AM, Bilgin M, Redmer S, Ostenfeld MS, Ulanet D, Dovmark TH, Lønborg A, Vindeløv SD, Hanahan D, Arenz C, Ejsing CS, Kirkegaard T, Rohde M, Nylandsted J, Jäättelä M. Petersen NH, et al. Among authors: rohde m. Cancer Cell. 2013 Sep 9;24(3):379-93. doi: 10.1016/j.ccr.2013.08.003. Cancer Cell. 2013. PMID: 24029234 Free article.
Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure.
Corcelle-Termeau E, Vindeløv SD, Hämälistö S, Mograbi B, Keldsbo A, Bräsen JH, Favaro E, Adam D, Szyniarowski P, Hofman P, Krautwald S, Farkas T, Petersen NH, Rohde M, Linkermann A, Jäättelä M. Corcelle-Termeau E, et al. Among authors: rohde m. Autophagy. 2016 May 3;12(5):833-49. doi: 10.1080/15548627.2016.1159378. Epub 2016 Apr 12. Autophagy. 2016. PMID: 27070082 Free PMC article.
1,064 results