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The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling.
Macheda ML, Sun WW, Kugathasan K, Hogan BM, Bower NI, Halford MM, Zhang YF, Jacques BE, Lieschke GJ, Dabdoub A, Stacker SA. Macheda ML, et al. Among authors: halford mm. J Biol Chem. 2012 Aug 24;287(35):29312-23. doi: 10.1074/jbc.M112.362681. Epub 2012 Jul 6. J Biol Chem. 2012. PMID: 22773843 Free PMC article.
Deficiency of the Wnt receptor Ryk causes multiple cardiac and outflow tract defects.
Kugathasan K, Halford MM, Farlie PG, Bates D, Smith DP, Zhang YF, Roy JP, Macheda ML, Zhang D, Wilkinson JL, Kirby ML, Newgreen DF, Stacker SA. Kugathasan K, et al. Among authors: halford mm. Growth Factors. 2018 Apr;36(1-2):58-68. doi: 10.1080/08977194.2018.1491848. Epub 2018 Jul 23. Growth Factors. 2018. PMID: 30035654
Revelations of the RYK receptor.
Halford MM, Stacker SA. Halford MM, et al. Bioessays. 2001 Jan;23(1):34-45. doi: 10.1002/1521-1878(200101)23:1<34::AID-BIES1005>3.0.CO;2-D. Bioessays. 2001. PMID: 11135307 Review.
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