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Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.
Himes BE, Jiang X, Hu R, Wu AC, Lasky-Su JA, Klanderman BJ, Ziniti J, Senter-Sylvia J, Lima JJ, Irvin CG, Peters SP, Meyers DA, Bleecker ER, Kubo M, Tamari M, Nakamura Y, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Hanrahan JP, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Panettieri RA Jr, Markezich A, Israel E, Carey VJ, Tantisira KG, Litonjua AA, Lu Q, Weiss ST. Himes BE, et al. Among authors: markezich a. PLoS Genet. 2012 Jul;8(7):e1002824. doi: 10.1371/journal.pgen.1002824. Epub 2012 Jul 5. PLoS Genet. 2012. PMID: 22792082 Free PMC article.
Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.
Tantisira KG, Damask A, Szefler SJ, Schuemann B, Markezich A, Su J, Klanderman B, Sylvia J, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Israel E; SHARP Investigators. Tantisira KG, et al. Among authors: markezich a. Am J Respir Crit Care Med. 2012 Jun 15;185(12):1286-91. doi: 10.1164/rccm.201111-2061OC. Epub 2012 Apr 26. Am J Respir Crit Care Med. 2012. PMID: 22538805 Free PMC article. Clinical Trial.
Genome-wide association study of short-acting β2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3.
Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG; SHARP Investigators. Israel E, et al. Among authors: markezich a. Am J Respir Crit Care Med. 2015 Mar 1;191(5):530-7. doi: 10.1164/rccm.201408-1426OC. Am J Respir Crit Care Med. 2015. PMID: 25562107 Free PMC article.
Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial.
Wechsler ME, Kunselman SJ, Chinchilli VM, Bleecker E, Boushey HA, Calhoun WJ, Ameredes BT, Castro M, Craig TJ, Denlinger L, Fahy JV, Jarjour N, Kazani S, Kim S, Kraft M, Lazarus SC, Lemanske RF Jr, Markezich A, Martin RJ, Permaul P, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Walter MJ, Wasserman SI, Israel E; National Heart, Lung and Blood Institute's Asthma Clinical Research Network. Wechsler ME, et al. Among authors: markezich a. Lancet. 2009 Nov 21;374(9703):1754-64. doi: 10.1016/S0140-6736(09)61492-6. Lancet. 2009. PMID: 19932356 Free PMC article. Clinical Trial.
A Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer.
Silvestri GA, Vachani A, Whitney D, Elashoff M, Porta Smith K, Ferguson JS, Parsons E, Mitra N, Brody J, Lenburg ME, Spira A; AEGIS Study Team. Silvestri GA, et al. N Engl J Med. 2015 Jul 16;373(3):243-51. doi: 10.1056/NEJMoa1504601. Epub 2015 May 17. N Engl J Med. 2015. PMID: 25981554 Free PMC article.