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A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice.
Mehrotra S, Al-Khami AA, Klarquist J, Husain S, Naga O, Eby JM, Murali AK, Lyons GE, Li M, Spivey ND, Norell H, Martins da Palma T, Onicescu G, Diaz-Montero CM, Garrett-Mayer E, Cole DJ, Le Poole IC, Nishimura MI. Mehrotra S, et al. Among authors: le poole ic. J Immunol. 2012 Aug 15;189(4):1627-38. doi: 10.4049/jimmunol.1103271. Epub 2012 Jul 13. J Immunol. 2012. PMID: 22798675 Free PMC article.
CCL22 to Activate Treg Migration and Suppress Depigmentation in Vitiligo.
Eby JM, Kang HK, Tully ST, Bindeman WE, Peiffer DS, Chatterjee S, Mehrotra S, Le Poole IC. Eby JM, et al. Among authors: le poole ic. J Invest Dermatol. 2015 Jun;135(6):1574-1580. doi: 10.1038/jid.2015.26. Epub 2015 Jan 9. J Invest Dermatol. 2015. PMID: 25634358 Free PMC article.
Functional cloning of a gp100-reactive T-cell receptor from vitiligo patient skin.
Klarquist J, Eby JM, Henning SW, Li M, Wainwright DA, Westerhof W, Luiten RM, Nishimura MI, Le Poole IC. Klarquist J, et al. Among authors: le poole ic. Pigment Cell Melanoma Res. 2016 May;29(3):379-84. doi: 10.1111/pcmr.12458. Epub 2016 Mar 4. Pigment Cell Melanoma Res. 2016. PMID: 26824221 Free PMC article.
Alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 can support immune responses toward tumors overexpressing ganglioside D3 in mice.
Eby JM, Barse L, Henning SW, Rabelink MJ, Klarquist J, Gilbert ER, Hammer AM, Fernandez MF, Yung N, Khan S, Miller HG, Kessler ER, Garrett-Mayer E, Dilling DF, Hoeben RC, Le Poole IC. Eby JM, et al. Among authors: le poole ic. Cancer Immunol Immunother. 2017 Jan;66(1):63-75. doi: 10.1007/s00262-016-1920-8. Epub 2016 Oct 27. Cancer Immunol Immunother. 2017. PMID: 27787577 Free PMC article.
Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.
Moore T, Wagner CR, Scurti GM, Hutchens KA, Godellas C, Clark AL, Kolawole EM, Hellman LM, Singh NK, Huyke FA, Wang SY, Calabrese KM, Embree HD, Orentas R, Shirai K, Dellacecca E, Garrett-Mayer E, Li M, Eby JM, Stiff PJ, Evavold BD, Baker BM, Le Poole IC, Dropulic B, Clark JI, Nishimura MI. Moore T, et al. Among authors: le poole ic. Cancer Immunol Immunother. 2018 Feb;67(2):311-325. doi: 10.1007/s00262-017-2073-0. Epub 2017 Oct 20. Cancer Immunol Immunother. 2018. PMID: 29052782 Free PMC article.
Molecular properties of gp100-reactive T-cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells.
Eby JM, Smith AR, Riley TP, Cosgrove C, Ankney CM, Henning SW, Paulos CM, Garrett-Mayer E, Luiten RM, Nishimura MI, Baker BM, Le Poole IC. Eby JM, et al. Among authors: le poole ic. Pigment Cell Melanoma Res. 2019 Jan;32(1):68-78. doi: 10.1111/pcmr.12724. Epub 2018 Aug 13. Pigment Cell Melanoma Res. 2019. PMID: 30009548 Free PMC article.
Antigen Specificity Enhances Disease Control by Tregs in Vitiligo.
Mukhatayev Z, Dellacecca ER, Cosgrove C, Shivde R, Jaishankar D, Pontarolo-Maag K, Eby JM, Henning SW, Ostapchuk YO, Cedercreutz K, Issanov A, Mehrotra S, Overbeck A, Junghans RP, Leventhal JR, Le Poole IC. Mukhatayev Z, et al. Among authors: le poole ic. Front Immunol. 2020 Dec 1;11:581433. doi: 10.3389/fimmu.2020.581433. eCollection 2020. Front Immunol. 2020. PMID: 33335528 Free PMC article.
Ccl22 Diverts T Regulatory Cells and Controls the Growth of Melanoma.
Klarquist J, Tobin K, Farhangi Oskuei P, Henning SW, Fernandez MF, Dellacecca ER, Navarro FC, Eby JM, Chatterjee S, Mehrotra S, Clark JI, Le Poole IC. Klarquist J, et al. Among authors: le poole ic. Cancer Res. 2016 Nov 1;76(21):6230-6240. doi: 10.1158/0008-5472.CAN-16-0618. Epub 2016 Sep 12. Cancer Res. 2016. PMID: 27634754 Free PMC article.
100 results