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The optimization of pyridazinone series of glucan synthase inhibitors.
Kuang R, Wu H, Ting PC, Aslanian RG, Cao J, Kim DW, Lee JF, Schwerdt J, Zhou G, Herr RJ, Zych AJ, Yang J, Lam SQ, Jenkins DM, Sakwa SA, Wainhaus S, Black TA, Cacciapuoti A, McNicholas PM, Xu Y, Walker SS. Kuang R, et al. Among authors: lam sq. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5268-71. doi: 10.1016/j.bmcl.2012.06.091. Epub 2012 Jul 4. Bioorg Med Chem Lett. 2012. PMID: 22818082
SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors.
Zhou G, Ting PC, Aslanian R, Cao J, Kim DW, Kuang R, Lee JF, Schwerdt J, Wu H, Herr RJ, Zych AJ, Yang J, Lam S, Wainhaus S, Black TA, McNicholas PM, Xu Y, Walker SS. Zhou G, et al. Bioorg Med Chem Lett. 2011 May 15;21(10):2890-3. doi: 10.1016/j.bmcl.2011.03.083. Epub 2011 Mar 30. Bioorg Med Chem Lett. 2011. PMID: 21489787