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Genetic association of CR1 with Alzheimer's disease: a tentative disease mechanism.
Hazrati LN, Van Cauwenberghe C, Brooks PL, Brouwers N, Ghani M, Sato C, Cruts M, Sleegers K, St George-Hyslop P, Van Broeckhoven C, Rogaeva E. Hazrati LN, et al. Among authors: van cauwenberghe c, van broeckhoven c. Neurobiol Aging. 2012 Dec;33(12):2949.e5-2949.e12. doi: 10.1016/j.neurobiolaging.2012.07.001. Epub 2012 Jul 21. Neurobiol Aging. 2012. PMID: 22819390
Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites.
Brouwers N, Van Cauwenberghe C, Engelborghs S, Lambert JC, Bettens K, Le Bastard N, Pasquier F, Montoya AG, Peeters K, Mattheijssens M, Vandenberghe R, Deyn PP, Cruts M, Amouyel P, Sleegers K, Van Broeckhoven C. Brouwers N, et al. Among authors: van cauwenberghe c, van broeckhoven c. Mol Psychiatry. 2012 Feb;17(2):223-33. doi: 10.1038/mp.2011.24. Epub 2011 Mar 15. Mol Psychiatry. 2012. PMID: 21403675 Free PMC article.
Complement receptor 1 coding variant p.Ser1610Thr in Alzheimer's disease and related endophenotypes.
Van Cauwenberghe C, Bettens K, Engelborghs S, Vandenbulcke M, Van Dongen J, Vermeulen S, Vandenberghe R, De Deyn PP, Van Broeckhoven C, Sleegers K. Van Cauwenberghe C, et al. Among authors: van dongen j, van broeckhoven c. Neurobiol Aging. 2013 Sep;34(9):2235.e1-6. doi: 10.1016/j.neurobiolaging.2013.03.008. Epub 2013 Apr 10. Neurobiol Aging. 2013. PMID: 23582656
Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study.
Cuyvers E, De Roeck A, Van den Bossche T, Van Cauwenberghe C, Bettens K, Vermeulen S, Mattheijssens M, Peeters K, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Van Broeckhoven C, Sleegers K. Cuyvers E, et al. Among authors: van cauwenberghe c, van den bossche t, van broeckhoven c. Lancet Neurol. 2015 Aug;14(8):814-822. doi: 10.1016/S1474-4422(15)00133-7. Epub 2015 Jun 30. Lancet Neurol. 2015. PMID: 26141617
Lymphoblast-derived integration-free iPSC lines from a female and male Alzheimer's disease patient expressing different copy numbers of a coding CNV in the Alzheimer risk gene CR1.
Schröter F, Sleegers K, Van Cauwenberghe C, Bohndorf M, Wruck W, Van Broeckhoven C, Adjaye J. Schröter F, et al. Among authors: van cauwenberghe c. Stem Cell Res. 2016 Nov;17(3):560-563. doi: 10.1016/j.scr.2016.10.003. Epub 2016 Oct 19. Stem Cell Res. 2016. PMID: 27789410 Free article.
C9orf72 G4C2 repeat expansions in Alzheimer's disease and mild cognitive impairment.
Cacace R, Van Cauwenberghe C, Bettens K, Gijselinck I, van der Zee J, Engelborghs S, Vandenbulcke M, Van Dongen J, Bäumer V, Dillen L, Mattheijssens M, Peeters K, Cruts M, Vandenberghe R, De Deyn PP, Van Broeckhoven C, Sleegers K. Cacace R, et al. Among authors: van cauwenberghe c, van der zee j, van dongen j, van broeckhoven c. Neurobiol Aging. 2013 Jun;34(6):1712.e1-7. doi: 10.1016/j.neurobiolaging.2012.12.019. Epub 2013 Jan 24. Neurobiol Aging. 2013. PMID: 23352322
A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ42.
Sleegers K, Bettens K, De Roeck A, Van Cauwenberghe C, Cuyvers E, Verheijen J, Struyfs H, Van Dongen J, Vermeulen S, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Van Broeckhoven C; BELNEU consortium. Sleegers K, et al. Among authors: van cauwenberghe c, van dongen j, van broeckhoven c. Alzheimers Dement. 2015 Dec;11(12):1452-1460. doi: 10.1016/j.jalz.2015.02.013. Epub 2015 Jun 15. Alzheimers Dement. 2015. PMID: 26086184 Free article.
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer's Disease; Alzheimer's Disease Genetic Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology; Moebus S, Mecocci P, Del Zo… See abstract for full author list ➔ Lambert JC, et al. Nat Genet. 2013 Dec;45(12):1452-8. doi: 10.1038/ng.2802. Epub 2013 Oct 27. Nat Genet. 2013. PMID: 24162737 Free PMC article.
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