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CDK6 binds and promotes the degradation of the EYA2 protein.
Kohrt D, Crary J, Zimmer M, Patrick AN, Ford HL, Hinds PW, Grossel MJ. Kohrt D, et al. Among authors: ford hl. Cell Cycle. 2014;13(1):62-71. doi: 10.4161/cc.26755. Epub 2013 Oct 12. Cell Cycle. 2014. PMID: 24196439 Free PMC article.
Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.
Krueger AB, Drasin DJ, Lea WA, Patrick AN, Patnaik S, Backos DS, Matheson CJ, Hu X, Barnaeva E, Holliday MJ, Blevins MA, Robin TP, Eisenmesser EZ, Ferrer M, Simeonov A, Southall N, Reigan P, Marugan J, Ford HL, Zhao R. Krueger AB, et al. Among authors: ford hl. J Biol Chem. 2014 Jun 6;289(23):16349-61. doi: 10.1074/jbc.M114.566729. Epub 2014 Apr 22. J Biol Chem. 2014. PMID: 24755226 Free PMC article.
The SIX1-EYA transcriptional complex as a therapeutic target in cancer.
Blevins MA, Towers CG, Patrick AN, Zhao R, Ford HL. Blevins MA, et al. Among authors: ford hl. Expert Opin Ther Targets. 2015 Feb;19(2):213-25. doi: 10.1517/14728222.2014.978860. Epub 2015 Jan 2. Expert Opin Ther Targets. 2015. PMID: 25555392 Free PMC article. Review.
The Eya phosphatase: Its unique role in cancer.
Zhou H, Zhang L, Vartuli RL, Ford HL, Zhao R. Zhou H, et al. Among authors: ford hl. Int J Biochem Cell Biol. 2018 Mar;96:165-170. doi: 10.1016/j.biocel.2017.09.001. Epub 2017 Sep 5. Int J Biochem Cell Biol. 2018. PMID: 28887153 Free PMC article. Review.
142 results