McKenna WG - Search Results

1

The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.

Prevo R, Fokas E, Reaper PM, Charlton PA, Pollard JR, McKenna WG, Muschel RJ, Brunner TB. Prevo R, et al. Among authors: mckenna wg. Cancer Biol Ther. 2012 Sep;13(11):1072-81. doi: 10.4161/cbt.21093. Epub 2012 Jul 24. Cancer Biol Ther. 2012. PMID: 22825331 Free PMC article.

2

Targeting radiation-resistant hypoxic tumour cells through ATR inhibition.

Pires IM, Olcina MM, Anbalagan S, Pollard JR, Reaper PM, Charlton PA, McKenna WG, Hammond EM. Pires IM, et al. Among authors: mckenna wg. Br J Cancer. 2012 Jul 10;107(2):291-9. doi: 10.1038/bjc.2012.265. Epub 2012 Jun 19. Br J Cancer. 2012. PMID: 22713662 Free PMC article.

3

Targeting tumor cells by enhancing radiation sensitivity.

McKenna WG, Muschel RJ. McKenna WG, et al. Genes Chromosomes Cancer. 2003 Dec;38(4):330-8. doi: 10.1002/gcc.10296. Genes Chromosomes Cancer. 2003. PMID: 14566853 Review.

4

Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras.

Brunner TB, Cengel KA, Hahn SM, Wu J, Fraker DL, McKenna WG, Bernhard EJ. Brunner TB, et al. Among authors: mckenna wg. Cancer Res. 2005 Sep 15;65(18):8433-41. doi: 10.1158/0008-5472.CAN-05-0158. Cancer Res. 2005. PMID: 16166322

5

A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.

Higgins GS, Prevo R, Lee YF, Helleday T, Muschel RJ, Taylor S, Yoshimura M, Hickson ID, Bernhard EJ, McKenna WG. Higgins GS, et al. Among authors: mckenna wg. Cancer Res. 2010 Apr 1;70(7):2984-93. doi: 10.1158/0008-5472.CAN-09-4040. Epub 2010 Mar 16. Cancer Res. 2010. PMID: 20233878 Free PMC article.

6

Dual inhibition of the PI3K/mTOR pathway increases tumor radiosensitivity by normalizing tumor vasculature.

Fokas E, Im JH, Hill S, Yameen S, Stratford M, Beech J, Hackl W, Maira SM, Bernhard EJ, McKenna WG, Muschel RJ. Fokas E, et al. Among authors: mckenna wg. Cancer Res. 2012 Jan 1;72(1):239-48. doi: 10.1158/0008-5472.CAN-11-2263. Epub 2011 Nov 22. Cancer Res. 2012. PMID: 22108822

7

NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity.

Fokas E, Yoshimura M, Prevo R, Higgins G, Hackl W, Maira SM, Bernhard EJ, McKenna WG, Muschel RJ. Fokas E, et al. Among authors: mckenna wg. Radiat Oncol. 2012 Mar 27;7:48. doi: 10.1186/1748-717X-7-48. Radiat Oncol. 2012. PMID: 22452803 Free PMC article.

8

The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies.

Fokas E, McKenna WG, Muschel RJ. Fokas E, et al. Among authors: mckenna wg. Cancer Metastasis Rev. 2012 Dec;31(3-4):823-42. doi: 10.1007/s10555-012-9394-4. Cancer Metastasis Rev. 2012. PMID: 22825313 Review.

9

Targeting ATR in DNA damage response and cancer therapeutics.

Fokas E, Prevo R, Hammond EM, Brunner TB, McKenna WG, Muschel RJ. Fokas E, et al. Among authors: mckenna wg. Cancer Treat Rev. 2014 Feb;40(1):109-17. doi: 10.1016/j.ctrv.2013.03.002. Epub 2013 Apr 11. Cancer Treat Rev. 2014. PMID: 23583268 Review.

10

Depletion of signal recognition particle 72kDa increases radiosensitivity.

Prevo R, Tiwana GS, Maughan TS, Buffa FM, McKenna WG, Higgins GS. Prevo R, et al. Among authors: mckenna wg. Cancer Biol Ther. 2017 Jun 3;18(6):425-432. doi: 10.1080/15384047.2017.1323587. Epub 2017 May 11. Cancer Biol Ther. 2017. PMID: 28494188 Free PMC article.

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