Helleday T - Search Results

1

The relationship between homologous recombination repair and the sensitivity of human epidermis to the size of daily doses over a 5-week course of breast radiotherapy.

Somaiah N, Yarnold J, Daley F, Pearson A, Gothard L, Rothkamm K, Helleday T. Somaiah N, et al. Among authors: helleday t. Clin Cancer Res. 2012 Oct 1;18(19):5479-88. doi: 10.1158/1078-0432.CCR-10-3297. Epub 2012 Aug 1. Clin Cancer Res. 2012. PMID: 22855580

2

DNA double-strand break repair: from mechanistic understanding to cancer treatment.

Helleday T, Lo J, van Gent DC, Engelward BP. Helleday T, et al. DNA Repair (Amst). 2007 Jul 1;6(7):923-35. doi: 10.1016/j.dnarep.2007.02.006. Epub 2007 Mar 23. DNA Repair (Amst). 2007. PMID: 17363343 Review.

3

Transcription-associated recombination is dependent on replication in Mammalian cells.

Gottipati P, Cassel TN, Savolainen L, Helleday T. Gottipati P, et al. Among authors: helleday t. Mol Cell Biol. 2008 Jan;28(1):154-64. doi: 10.1128/MCB.00816-07. Epub 2007 Oct 29. Mol Cell Biol. 2008. PMID: 17967877 Free PMC article.

4

A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.

Higgins GS, Prevo R, Lee YF, Helleday T, Muschel RJ, Taylor S, Yoshimura M, Hickson ID, Bernhard EJ, McKenna WG. Higgins GS, et al. Among authors: helleday t. Cancer Res. 2010 Apr 1;70(7):2984-93. doi: 10.1158/0008-5472.CAN-09-4040. Epub 2010 Mar 16. Cancer Res. 2010. PMID: 20233878 Free PMC article.

5

Homologous recombination in cancer development, treatment and development of drug resistance.

Helleday T. Helleday T. Carcinogenesis. 2010 Jun;31(6):955-60. doi: 10.1093/carcin/bgq064. Epub 2010 Mar 29. Carcinogenesis. 2010. PMID: 20351092 Review.

6

Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells.

Gottipati P, Vischioni B, Schultz N, Solomons J, Bryant HE, Djureinovic T, Issaeva N, Sleeth K, Sharma RA, Helleday T. Gottipati P, et al. Among authors: helleday t. Cancer Res. 2010 Jul 1;70(13):5389-98. doi: 10.1158/0008-5472.CAN-09-4716. Epub 2010 Jun 15. Cancer Res. 2010. PMID: 20551068 Free article.

7

Targeting homologous recombination repair defects in cancer.

Evers B, Helleday T, Jonkers J. Evers B, et al. Among authors: helleday t. Trends Pharmacol Sci. 2010 Aug;31(8):372-80. doi: 10.1016/j.tips.2010.06.001. Epub 2010 Jul 2. Trends Pharmacol Sci. 2010. PMID: 20598756 Review.

8

Overexpression of POLQ confers a poor prognosis in early breast cancer patients.

Higgins GS, Harris AL, Prevo R, Helleday T, McKenna WG, Buffa FM. Higgins GS, et al. Among authors: helleday t. Oncotarget. 2010 Jul;1(3):175-84. doi: 10.18632/oncotarget.124. Oncotarget. 2010. PMID: 20700469 Free PMC article.

9

Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment.

Chan N, Pires IM, Bencokova Z, Coackley C, Luoto KR, Bhogal N, Lakshman M, Gottipati P, Oliver FJ, Helleday T, Hammond EM, Bristow RG. Chan N, et al. Among authors: helleday t. Cancer Res. 2010 Oct 15;70(20):8045-54. doi: 10.1158/0008-5472.CAN-10-2352. Epub 2010 Oct 5. Cancer Res. 2010. PMID: 20924112 Free PMC article.

10

Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells.

Bauerschmidt C, Woodcock M, Stevens DL, Hill MA, Rothkamm K, Helleday T. Bauerschmidt C, et al. Among authors: helleday t. Exp Cell Res. 2011 Feb 1;317(3):330-7. doi: 10.1016/j.yexcr.2010.10.021. Epub 2010 Nov 4. Exp Cell Res. 2011. PMID: 21056556 Free PMC article.

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