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Identification of a unique TGF-β-dependent molecular and functional signature in microglia.
Butovsky O, Jedrychowski MP, Moore CS, Cialic R, Lanser AJ, Gabriely G, Koeglsperger T, Dake B, Wu PM, Doykan CE, Fanek Z, Liu L, Chen Z, Rothstein JD, Ransohoff RM, Gygi SP, Antel JP, Weiner HL. Butovsky O, et al. Nat Neurosci. 2014 Jan;17(1):131-43. doi: 10.1038/nn.3599. Epub 2013 Dec 8. Nat Neurosci. 2014. PMID: 24316888 Free PMC article.
Differential roles of microglia and monocytes in the inflamed central nervous system.
Yamasaki R, Lu H, Butovsky O, Ohno N, Rietsch AM, Cialic R, Wu PM, Doykan CE, Lin J, Cotleur AC, Kidd G, Zorlu MM, Sun N, Hu W, Liu L, Lee JC, Taylor SE, Uehlein L, Dixon D, Gu J, Floruta CM, Zhu M, Charo IF, Weiner HL, Ransohoff RM. Yamasaki R, et al. Among authors: butovsky o. J Exp Med. 2014 Jul 28;211(8):1533-49. doi: 10.1084/jem.20132477. Epub 2014 Jul 7. J Exp Med. 2014. PMID: 25002752 Free PMC article.
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
Butovsky O, Jedrychowski MP, Cialic R, Krasemann S, Murugaiyan G, Fanek Z, Greco DJ, Wu PM, Doykan CE, Kiner O, Lawson RJ, Frosch MP, Pochet N, Fatimy RE, Krichevsky AM, Gygi SP, Lassmann H, Berry J, Cudkowicz ME, Weiner HL. Butovsky O, et al. Ann Neurol. 2015 Jan;77(1):75-99. doi: 10.1002/ana.24304. Epub 2014 Nov 27. Ann Neurol. 2015. PMID: 25381879 Free PMC article.
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z, Greco DJ, Smith ST, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich JD, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner FL, Litvak V, Holtzman DM, Lassmann H, Weiner HL, Ochando J, Haass C, Butovsky O. Krasemann S, et al. Among authors: butovsky o, o loughlin e. Immunity. 2017 Sep 19;47(3):566-581.e9. doi: 10.1016/j.immuni.2017.08.008. Immunity. 2017. PMID: 28930663 Free PMC article.
Pro-inflammatory activation of microglia in the brain of patients with sepsis.
Zrzavy T, Höftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, Lassmann H. Zrzavy T, et al. Among authors: butovsky o. Neuropathol Appl Neurobiol. 2019 Apr;45(3):278-290. doi: 10.1111/nan.12502. Epub 2018 Jun 19. Neuropathol Appl Neurobiol. 2019. PMID: 29804289 Free PMC article.
Microglia inhibit photoreceptor cell death and regulate immune cell infiltration in response to retinal detachment.
Okunuki Y, Mukai R, Pearsall EA, Klokman G, Husain D, Park DH, Korobkina E, Weiner HL, Butovsky O, Ksander BR, Miller JW, Connor KM. Okunuki Y, et al. Among authors: butovsky o. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6264-E6273. doi: 10.1073/pnas.1719601115. Epub 2018 Jun 18. Proc Natl Acad Sci U S A. 2018. PMID: 29915052 Free PMC article.
88 results