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Brca1 required for T cell lineage development but not TCR loci rearrangement.
Mak TW, Hakem A, McPherson JP, Shehabeldin A, Zablocki E, Migon E, Duncan GS, Bouchard D, Wakeham A, Cheung A, Karaskova J, Sarosi I, Squire J, Marth J, Hakem R. Mak TW, et al. Among authors: wakeham a. Nat Immunol. 2000 Jul;1(1):77-82. doi: 10.1038/76950. Nat Immunol. 2000. PMID: 10881179
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death.
Joza N, Susin SA, Daugas E, Stanford WL, Cho SK, Li CY, Sasaki T, Elia AJ, Cheng HY, Ravagnan L, Ferri KF, Zamzami N, Wakeham A, Hakem R, Yoshida H, Kong YY, Mak TW, Zúñiga-Pflücker JC, Kroemer G, Penninger JM. Joza N, et al. Among authors: wakeham a. Nature. 2001 Mar 29;410(6828):549-54. doi: 10.1038/35069004. Nature. 2001. PMID: 11279485
ICOS is essential for effective T-helper-cell responses.
Tafuri A, Shahinian A, Bladt F, Yoshinaga SK, Jordana M, Wakeham A, Boucher LM, Bouchard D, Chan VS, Duncan G, Odermatt B, Ho A, Itie A, Horan T, Whoriskey JS, Pawson T, Penninger JM, Ohashi PS, Mak TW. Tafuri A, et al. Among authors: wakeham a. Nature. 2001 Jan 4;409(6816):105-9. doi: 10.1038/35051113. Nature. 2001. PMID: 11343123
Generation and characterization of Smac/DIABLO-deficient mice.
Okada H, Suh WK, Jin J, Woo M, Du C, Elia A, Duncan GS, Wakeham A, Itie A, Lowe SW, Wang X, Mak TW. Okada H, et al. Among authors: wakeham a. Mol Cell Biol. 2002 May;22(10):3509-17. doi: 10.1128/MCB.22.10.3509-3517.2002. Mol Cell Biol. 2002. PMID: 11971981 Free PMC article.
Role of SODD in regulation of tumor necrosis factor responses.
Takada H, Chen NJ, Mirtsos C, Suzuki S, Suzuki N, Wakeham A, Mak TW, Yeh WC. Takada H, et al. Among authors: wakeham a. Mol Cell Biol. 2003 Jun;23(11):4026-33. doi: 10.1128/MCB.23.11.4026-4033.2003. Mol Cell Biol. 2003. PMID: 12748303 Free PMC article.
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses.
Mak TW, Shahinian A, Yoshinaga SK, Wakeham A, Boucher LM, Pintilie M, Duncan G, Gajewska BU, Gronski M, Eriksson U, Odermatt B, Ho A, Bouchard D, Whorisky JS, Jordana M, Ohashi PS, Pawson T, Bladt F, Tafuri A. Mak TW, et al. Among authors: wakeham a. Nat Immunol. 2003 Aug;4(8):765-72. doi: 10.1038/ni947. Epub 2003 Jun 29. Nat Immunol. 2003. PMID: 12833154
138 results