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Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks.
Ramanan VK, Kim S, Holohan K, Shen L, Nho K, Risacher SL, Foroud TM, Mukherjee S, Crane PK, Aisen PS, Petersen RC, Weiner MW, Saykin AJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI). Ramanan VK, et al. Among authors: aisen ps. Brain Imaging Behav. 2012 Dec;6(4):634-48. doi: 10.1007/s11682-012-9196-x. Brain Imaging Behav. 2012. PMID: 22865056 Free PMC article.
Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials.
Grundman M, Petersen RC, Ferris SH, Thomas RG, Aisen PS, Bennett DA, Foster NL, Jack CR Jr, Galasko DR, Doody R, Kaye J, Sano M, Mohs R, Gauthier S, Kim HT, Jin S, Schultz AN, Schafer K, Mulnard R, van Dyck CH, Mintzer J, Zamrini EY, Cahn-Weiner D, Thal LJ; Alzheimer's Disease Cooperative Study. Grundman M, et al. Among authors: aisen ps. Arch Neurol. 2004 Jan;61(1):59-66. doi: 10.1001/archneur.61.1.59. Arch Neurol. 2004. PMID: 14732621 Clinical Trial.
Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study.
Doody RS, Gavrilova SI, Sano M, Thomas RG, Aisen PS, Bachurin SO, Seely L, Hung D; dimebon investigators. Doody RS, et al. Among authors: aisen ps. Lancet. 2008 Jul 19;372(9634):207-15. doi: 10.1016/S0140-6736(08)61074-0. Lancet. 2008. PMID: 18640457 Clinical Trial.
Multi-modal imaging predicts memory performance in normal aging and cognitive decline.
Walhovd KB, Fjell AM, Dale AM, McEvoy LK, Brewer J, Karow DS, Salmon DP, Fennema-Notestine C; Alzheimer's Disease Neuroimaging Initiative. Walhovd KB, et al. Neurobiol Aging. 2010 Jul;31(7):1107-21. doi: 10.1016/j.neurobiolaging.2008.08.013. Epub 2008 Oct 5. Neurobiol Aging. 2010. PMID: 18838195 Free PMC article.
627 results