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Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes.
Howson JM, Cooper JD, Smyth DJ, Walker NM, Stevens H, She JX, Eisenbarth GS, Rewers M, Todd JA, Akolkar B, Concannon P, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Pociot F, Rich SS; Type 1 Diabetes Genetics Consortium. Howson JM, et al. Among authors: smyth dj. Diabetes. 2012 Nov;61(11):3012-7. doi: 10.2337/db11-1694. Epub 2012 Aug 13. Diabetes. 2012. PMID: 22891215 Free PMC article.
Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes.
Bailey R, Cooper JD, Zeitels L, Smyth DJ, Yang JH, Walker NM, Hyppönen E, Dunger DB, Ramos-Lopez E, Badenhoop K, Nejentsev S, Todd JA. Bailey R, et al. Among authors: smyth dj. Diabetes. 2007 Oct;56(10):2616-21. doi: 10.2337/db07-0652. Epub 2007 Jul 2. Diabetes. 2007. PMID: 17606874 Free PMC article.
A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3.
Concannon P, Onengut-Gumuscu S, Todd JA, Smyth DJ, Pociot F, Bergholdt R, Akolkar B, Erlich HA, Hilner JE, Julier C, Morahan G, Nerup J, Nierras CR, Chen WM, Rich SS; Type 1 Diabetes Genetics Consortium. Concannon P, et al. Among authors: smyth dj. Diabetes. 2008 Oct;57(10):2858-61. doi: 10.2337/db08-0753. Epub 2008 Jul 22. Diabetes. 2008. PMID: 18647951 Free PMC article.
Shared and distinct genetic variants in type 1 diabetes and celiac disease.
Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JH, Howson JM, Stevens H, McManus R, Wijmenga C, Heap GA, Dubois PC, Clayton DG, Hunt KA, van Heel DA, Todd JA. Smyth DJ, et al. N Engl J Med. 2008 Dec 25;359(26):2767-77. doi: 10.1056/NEJMoa0807917. Epub 2008 Dec 10. N Engl J Med. 2008. PMID: 19073967 Free PMC article.
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; Type 1 Diabetes Genetics Consortium. Barrett JC, et al. Among authors: smyth dj. Nat Genet. 2009 Jun;41(6):703-7. doi: 10.1038/ng.381. Epub 2009 May 10. Nat Genet. 2009. PMID: 19430480 Free PMC article.
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
Plagnol V, Howson JM, Smyth DJ, Walker N, Hafler JP, Wallace C, Stevens H, Jackson L, Simmonds MJ; Type 1 Diabetes Genetics Consortium; Bingley PJ, Gough SC, Todd JA. Plagnol V, et al. Among authors: smyth dj. PLoS Genet. 2011 Aug;7(8):e1002216. doi: 10.1371/journal.pgen.1002216. Epub 2011 Aug 4. PLoS Genet. 2011. PMID: 21829393 Free PMC article.
129 results