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Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development.
Lage K, Greenway SC, Rosenfeld JA, Wakimoto H, Gorham JM, Segrè AV, Roberts AE, Smoot LB, Pu WT, Pereira AC, Mesquita SM, Tommerup N, Brunak S, Ballif BC, Shaffer LG, Donahoe PK, Daly MJ, Seidman JG, Seidman CE, Larsen LA. Lage K, et al. Among authors: donahoe pk. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14035-40. doi: 10.1073/pnas.1210730109. Epub 2012 Aug 16. Proc Natl Acad Sci U S A. 2012. PMID: 22904188 Free PMC article.
SRY recognizes conserved DNA sites in sex-specific promoters.
Haqq CM, King CY, Donahoe PK, Weiss MA. Haqq CM, et al. Among authors: donahoe pk. Proc Natl Acad Sci U S A. 1993 Feb 1;90(3):1097-101. doi: 10.1073/pnas.90.3.1097. Proc Natl Acad Sci U S A. 1993. PMID: 8430080 Free PMC article.
HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis.
Hayashida T, Takahashi F, Chiba N, Brachtel E, Takahashi M, Godin-Heymann N, Gross KW, Vivanco Md, Wijendran V, Shioda T, Sgroi D, Donahoe PK, Maheswaran S. Hayashida T, et al. Among authors: donahoe pk. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1100-5. doi: 10.1073/pnas.0912710107. Epub 2009 Dec 28. Proc Natl Acad Sci U S A. 2010. PMID: 20080567 Free PMC article.
Dissecting spatio-temporal protein networks driving human heart development and related disorders.
Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham JM, Workman CT, Bendsen E, Hansen NT, Rigina O, Roque FS, Wiese C, Christoffels VM, Roberts AE, Smoot LB, Pu WT, Donahoe PK, Tommerup N, Brunak S, Seidman CE, Seidman JG, Larsen LA. Lage K, et al. Among authors: donahoe pk. Mol Syst Biol. 2010 Jun 22;6:381. doi: 10.1038/msb.2010.36. Mol Syst Biol. 2010. PMID: 20571530 Free PMC article.
Mullerian inhibiting substance preferentially inhibits stem/progenitors in human ovarian cancer cell lines compared with chemotherapeutics.
Wei X, Dombkowski D, Meirelles K, Pieretti-Vanmarcke R, Szotek PP, Chang HL, Preffer FI, Mueller PR, Teixeira J, MacLaughlin DT, Donahoe PK. Wei X, et al. Among authors: donahoe pk. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18874-9. doi: 10.1073/pnas.1012667107. Epub 2010 Oct 15. Proc Natl Acad Sci U S A. 2010. PMID: 20952655 Free PMC article.
Human ovarian cancer stem/progenitor cells are stimulated by doxorubicin but inhibited by Mullerian inhibiting substance.
Meirelles K, Benedict LA, Dombkowski D, Pepin D, Preffer FI, Teixeira J, Tanwar PS, Young RH, MacLaughlin DT, Donahoe PK, Wei X. Meirelles K, et al. Among authors: donahoe pk. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2358-63. doi: 10.1073/pnas.1120733109. Epub 2012 Jan 27. Proc Natl Acad Sci U S A. 2012. PMID: 22308459 Free PMC article.
Congenital diaphragmatic hernia candidate genes derived from embryonic transcriptomes.
Russell MK, Longoni M, Wells J, Maalouf FI, Tracy AA, Loscertales M, Ackerman KG, Pober BR, Lage K, Bult CJ, Donahoe PK. Russell MK, et al. Among authors: donahoe pk. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2978-83. doi: 10.1073/pnas.1121621109. Epub 2012 Feb 6. Proc Natl Acad Sci U S A. 2012. PMID: 22315423 Free PMC article.
342 results