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Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development.
Lage K, Greenway SC, Rosenfeld JA, Wakimoto H, Gorham JM, Segrè AV, Roberts AE, Smoot LB, Pu WT, Pereira AC, Mesquita SM, Tommerup N, Brunak S, Ballif BC, Shaffer LG, Donahoe PK, Daly MJ, Seidman JG, Seidman CE, Larsen LA. Lage K, et al. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14035-40. doi: 10.1073/pnas.1210730109. Epub 2012 Aug 16. Proc Natl Acad Sci U S A. 2012. PMID: 22904188 Free PMC article.
Dissecting spatio-temporal protein networks driving human heart development and related disorders.
Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham JM, Workman CT, Bendsen E, Hansen NT, Rigina O, Roque FS, Wiese C, Christoffels VM, Roberts AE, Smoot LB, Pu WT, Donahoe PK, Tommerup N, Brunak S, Seidman CE, Seidman JG, Larsen LA. Lage K, et al. Mol Syst Biol. 2010 Jun 22;6:381. doi: 10.1038/msb.2010.36. Mol Syst Biol. 2010. PMID: 20571530 Free PMC article.
Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis.
Berchtold LA, Størling ZM, Ortis F, Lage K, Bang-Berthelsen C, Bergholdt R, Hald J, Brorsson CA, Eizirik DL, Pociot F, Brunak S, Størling J. Berchtold LA, et al. Among authors: lage k. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):E681-8. doi: 10.1073/pnas.1104384108. Epub 2011 Jun 24. Proc Natl Acad Sci U S A. 2011. PMID: 21705657 Free PMC article.
Pervasive sharing of genetic effects in autoimmune disease.
Cotsapas C, Voight BF, Rossin E, Lage K, Neale BM, Wallace C, Abecasis GR, Barrett JC, Behrens T, Cho J, De Jager PL, Elder JT, Graham RR, Gregersen P, Klareskog L, Siminovitch KA, van Heel DA, Wijmenga C, Worthington J, Todd JA, Hafler DA, Rich SS, Daly MJ; FOCiS Network of Consortia. Cotsapas C, et al. Among authors: lage k. PLoS Genet. 2011 Aug;7(8):e1002254. doi: 10.1371/journal.pgen.1002254. Epub 2011 Aug 10. PLoS Genet. 2011. PMID: 21852963 Free PMC article.
83 results