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Tear lacritin levels by age, sex, and time of day in healthy adults.
Seifert K, Gandia NC, Wilburn JK, Bower KS, Sia RK, Ryan DS, Deaton ML, Still KM, Vassilev VC, Laurie GW, McKown RL. Seifert K, et al. Among authors: laurie gw. Invest Ophthalmol Vis Sci. 2012 Sep 25;53(10):6610-6. doi: 10.1167/iovs.11-8729. Invest Ophthalmol Vis Sci. 2012. PMID: 22918641 Free PMC article.
Development of a Quantitative Immunoassay for Tear Lacritin Proteoforms.
Justis BM, Coburn CE, Tyler EM, Showalter RS, Dissler BJ, Li M, McNamara NA, Laurie GW, McKown RL. Justis BM, et al. Among authors: laurie gw. Transl Vis Sci Technol. 2020 Aug 6;9(9):13. doi: 10.1167/tvst.9.9.13. eCollection 2020 Aug. Transl Vis Sci Technol. 2020. PMID: 32879769 Free PMC article.
Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis.
Georgiev GA, Gh MS, Romano J, Dias Teixeira KL, Struble C, Ryan DS, Sia RK, Kitt JP, Harris JM, Hsu KL, Libby A, Odrich MG, Suárez T, McKown RL, Laurie GW. Georgiev GA, et al. Among authors: laurie gw. J Biol Chem. 2021 Jan-Jun;296:100070. doi: 10.1074/jbc.RA120.015833. Epub 2020 Nov 21. J Biol Chem. 2021. PMID: 33187980 Free PMC article.
Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity.
Velez V F, Romano JA, McKown RL, Green K, Zhang L, Raab RW, Ryan DS, Hutnik CM, Frierson HF Jr, Laurie GW. Velez V F, et al. Among authors: laurie gw. Invest Ophthalmol Vis Sci. 2013 Mar 1;54(3):2123-32. doi: 10.1167/iovs.12-11488. Invest Ophthalmol Vis Sci. 2013. PMID: 23425695 Free PMC article.
A cleavage-potentiated fragment of tear lacritin is bactericidal.
McKown RL, Coleman Frazier EV, Zadrozny KK, Deleault AM, Raab RW, Ryan DS, Sia RK, Lee JK, Laurie GW. McKown RL, et al. Among authors: laurie gw. J Biol Chem. 2014 Aug 8;289(32):22172-82. doi: 10.1074/jbc.M114.570143. Epub 2014 Jun 18. J Biol Chem. 2014. PMID: 24942736 Free PMC article.
The Lacritin-Syndecan-1-Heparanase Axis in Dry Eye Disease.
Dias-Teixeira K, Horton X, McKown R, Romano J, Laurie GW. Dias-Teixeira K, et al. Among authors: laurie gw. Adv Exp Med Biol. 2020;1221:747-757. doi: 10.1007/978-3-030-34521-1_31. Adv Exp Med Biol. 2020. PMID: 32274735 Free PMC article. Review.
82 results