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Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment.
Coussens AK, Wilkinson RJ, Hanifa Y, Nikolayevskyy V, Elkington PT, Islam K, Timms PM, Venton TR, Bothamley GH, Packe GE, Darmalingam M, Davidson RN, Milburn HJ, Baker LV, Barker RD, Mein CA, Bhaw-Rosun L, Nuamah R, Young DB, Drobniewski FA, Griffiths CJ, Martineau AR. Coussens AK, et al. Among authors: elkington pt. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15449-54. doi: 10.1073/pnas.1200072109. Epub 2012 Sep 4. Proc Natl Acad Sci U S A. 2012. PMID: 22949664 Free PMC article. Clinical Trial.
Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10.
Ahmed M, Mackenzie J, Tezera L, Krause R, Truebody B, Garay-Baquero D, Vallejo A, Govender K, Adamson J, Fisher H, Essex JW, Mansour S, Elkington P, Steyn AJC, Leslie A. Ahmed M, et al. Commun Biol. 2022 Dec 1;5(1):1317. doi: 10.1038/s42003-022-04265-0. Commun Biol. 2022. PMID: 36456824 Free PMC article.
Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases.
Walker NF, Clark SO, Oni T, Andreu N, Tezera L, Singh S, Saraiva L, Pedersen B, Kelly DL, Tree JA, D'Armiento JM, Meintjes G, Mauri FA, Williams A, Wilkinson RJ, Friedland JS, Elkington PT. Walker NF, et al. Among authors: elkington pt. Am J Respir Crit Care Med. 2012 May 1;185(9):989-97. doi: 10.1164/rccm.201110-1769OC. Epub 2012 Feb 16. Am J Respir Crit Care Med. 2012. PMID: 22345579 Free PMC article.
Ethnic variation in inflammatory profile in tuberculosis.
Coussens AK, Wilkinson RJ, Nikolayevskyy V, Elkington PT, Hanifa Y, Islam K, Timms PM, Bothamley GH, Claxton AP, Packe GE, Darmalingam M, Davidson RN, Milburn HJ, Baker LV, Barker RD, Drobniewski FA, Mein CA, Bhaw-Rosun L, Nuamah RA, Griffiths CJ, Martineau AR. Coussens AK, et al. Among authors: elkington pt. PLoS Pathog. 2013;9(7):e1003468. doi: 10.1371/journal.ppat.1003468. Epub 2013 Jul 4. PLoS Pathog. 2013. PMID: 23853590 Free PMC article.
Towards host-directed therapies for tuberculosis.
Zumla A, Maeurer M; Host-Directed Therapies Network; Chakaya J, Hoelscher M, Ntoumi F, Rustomjee R, Vilaplana C, Yeboah-Manu D, Rasolof V, Munderi P, Singh N, Aklillu E, Padayatchi N, Macete E, Kapata N, Mulenga M, Kibiki G, Mfinanga S, Nyirenda T, Maboko L, Garcia-Basteiro A, Rakotosamimanana N, Bates M, Mwaba P, Reither K, Gagneux S, Edwards S, Mfinanga E, Abdulla S, Cardona PJ, Russell JB, Gant V, Noursadeghi M, Elkington P, Bonnet M, Menendez C, Dieye TN, Diarra B, Maiga A, Aseffa A, Parida S, Wejse C, Petersen E, Kaleebu P, Oliver M, Craig G, Corrah T, Tientcheu L, Antonio M, Rao M, McHugh TD, Sheikh A, Ippolito G, Ramjee G, Kaufmann SH, Churchyard G, Steyn A, Grobusch M, Sanne I, Martinson N, Madansein R, Wilkinson RJ, Mayosi B, Schito M, Wallis RS. Zumla A, et al. Nat Rev Drug Discov. 2015 Aug;14(8):511-2. doi: 10.1038/nrd4696. Epub 2015 Jul 17. Nat Rev Drug Discov. 2015. PMID: 26184493 Free article.
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