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Genetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.
Pollin TI, Isakova T, Jablonski KA, de Bakker PI, Taylor A, McAteer J, Pan Q, Horton ES, Delahanty LM, Altshuler D, Shuldiner AR, Goldberg RB, Florez JC, Franks PW; Diabetes Prevention Program Research Group. Pollin TI, et al. Among authors: altshuler d. PLoS Genet. 2012;8(8):e1002895. doi: 10.1371/journal.pgen.1002895. Epub 2012 Aug 30. PLoS Genet. 2012. PMID: 22951888 Free PMC article.
Efficiency and power in genetic association studies.
de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, Altshuler D. de Bakker PI, et al. Among authors: altshuler d. Nat Genet. 2005 Nov;37(11):1217-23. doi: 10.1038/ng1669. Epub 2005 Oct 23. Nat Genet. 2005. PMID: 16244653
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program.
Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, Knowler WC, Nathan DM, Altshuler D; Diabetes Prevention Program Research Group. Florez JC, et al. Among authors: altshuler d. N Engl J Med. 2006 Jul 20;355(3):241-50. doi: 10.1056/NEJMoa062418. N Engl J Med. 2006. PMID: 16855264 Free PMC article.
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.
Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, Sjögren M, Florez JC, Almgren P, Isomaa B, Orho-Melander M, Lindblad U, Daly MJ, Tuomi T, Hirschhorn JN, Ardlie KG, Groop LC, Altshuler D. Saxena R, et al. Among authors: altshuler d. Diabetes. 2006 Oct;55(10):2890-5. doi: 10.2337/db06-0381. Diabetes. 2006. PMID: 17003358
490 results