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Sorafenib has potent antitumor activity against multiple myeloma in vitro, ex vivo, and in vivo in the 5T33MM mouse model.
Kharaziha P, De Raeve H, Fristedt C, Li Q, Gruber A, Johnsson P, Kokaraki G, Panzar M, Laane E, Osterborg A, Zhivotovsky B, Jernberg-Wiklund H, Grandér D, Celsing F, Björkholm M, Vanderkerken K, Panaretakis T. Kharaziha P, et al. Cancer Res. 2012 Oct 15;72(20):5348-62. doi: 10.1158/0008-5472.CAN-12-0658. Epub 2012 Sep 4. Cancer Res. 2012. PMID: 22952216
Multitargeted therapies for multiple myeloma.
Kharaziha P, Ceder S, Sanchez C, Panaretakis T. Kharaziha P, et al. Autophagy. 2013 Feb 1;9(2):255-7. doi: 10.4161/auto.22738. Epub 2012 Nov 26. Autophagy. 2013. PMID: 23183549 Free PMC article.
Sorafenib-induced defective autophagy promotes cell death by necroptosis.
Kharaziha P, Chioureas D, Baltatzis G, Fonseca P, Rodriguez P, Gogvadze V, Lennartsson L, Björklund AC, Zhivotovsky B, Grandér D, Egevad L, Nilsson S, Panaretakis T. Kharaziha P, et al. Oncotarget. 2015 Nov 10;6(35):37066-82. doi: 10.18632/oncotarget.5797. Oncotarget. 2015. PMID: 26416459 Free PMC article.
Tumor cell-derived exosomes: a message in a bottle.
Kharaziha P, Ceder S, Li Q, Panaretakis T. Kharaziha P, et al. Biochim Biophys Acta. 2012 Aug;1826(1):103-11. doi: 10.1016/j.bbcan.2012.03.006. Epub 2012 Apr 1. Biochim Biophys Acta. 2012. PMID: 22503823 Review.
Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy.
Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Oscarsson J, Corcoran M, Björklund AC, Hultenby K, Lundin J, Heyman M, Söderhäll S, Mazur J, Porwit A, Pandolfi PP, Zhivotovsky B, Panaretakis T, Grandér D. Laane E, et al. Among authors: kharaziha p. Cell Death Differ. 2009 Jul;16(7):1018-29. doi: 10.1038/cdd.2009.46. Epub 2009 Apr 24. Cell Death Differ. 2009. PMID: 19390558
Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells.
Pellegrini P, Dyczynski M, Sbrana FV, Karlgren M, Buoncervello M, Hägg-Olofsson M, Ma R, Hartman J, Bajalica-Lagercrantz S, Grander D, Kharaziha P, De Milito A. Pellegrini P, et al. Among authors: kharaziha p. Oncotarget. 2016 Jun 14;7(24):35703-35723. doi: 10.18632/oncotarget.9601. Oncotarget. 2016. PMID: 27248168 Free PMC article.
23 results