Panaretakis T - Search Results

1

Sorafenib has potent antitumor activity against multiple myeloma in vitro, ex vivo, and in vivo in the 5T33MM mouse model.

Kharaziha P, De Raeve H, Fristedt C, Li Q, Gruber A, Johnsson P, Kokaraki G, Panzar M, Laane E, Osterborg A, Zhivotovsky B, Jernberg-Wiklund H, Grandér D, Celsing F, Björkholm M, Vanderkerken K, Panaretakis T. Kharaziha P, et al. Among authors: panaretakis t. Cancer Res. 2012 Oct 15;72(20):5348-62. doi: 10.1158/0008-5472.CAN-12-0658. Epub 2012 Sep 4. Cancer Res. 2012. PMID: 22952216

2

Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid.

Panaretakis T, Shabalina IG, Grandér D, Shoshan MC, DePierre JW. Panaretakis T, et al. Toxicol Appl Pharmacol. 2001 May 15;173(1):56-64. doi: 10.1006/taap.2001.9159. Toxicol Appl Pharmacol. 2001. PMID: 11350215

3

Activation of Bak, Bax, and BH3-only proteins in the apoptotic response to doxorubicin.

Panaretakis T, Pokrovskaja K, Shoshan MC, Grandér D. Panaretakis T, et al. J Biol Chem. 2002 Nov 15;277(46):44317-26. doi: 10.1074/jbc.M205273200. Epub 2002 Aug 21. J Biol Chem. 2002. PMID: 12193597 Free article.

4

Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.

Panaretakis T, Pokrovskaja K, Shoshan MC, Grandér D. Panaretakis T, et al. Oncogene. 2003 Jul 17;22(29):4543-56. doi: 10.1038/sj.onc.1206503. Oncogene. 2003. PMID: 12881711

5

Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway.

Thyrell L, Hjortsberg L, Arulampalam V, Panaretakis T, Uhles S, Dagnell M, Zhivotovsky B, Leibiger I, Grandér D, Pokrovskaja K. Thyrell L, et al. Among authors: panaretakis t. J Biol Chem. 2004 Jun 4;279(23):24152-62. doi: 10.1074/jbc.M312219200. Epub 2004 Mar 31. J Biol Chem. 2004. PMID: 15056668 Free article.

6

Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis.

Panaretakis T, Laane E, Pokrovskaja K, Björklund AC, Moustakas A, Zhivotovsky B, Heyman M, Shoshan MC, Grandér D. Panaretakis T, et al. Mol Biol Cell. 2005 Aug;16(8):3821-31. doi: 10.1091/mbc.e04-10-0862. Epub 2005 May 25. Mol Biol Cell. 2005. PMID: 15917298 Free PMC article.

7

Alternative signaling pathways regulating type I interferon-induced apoptosis.

Pokrovskaja K, Panaretakis T, Grandér D. Pokrovskaja K, et al. Among authors: panaretakis t. J Interferon Cytokine Res. 2005 Dec;25(12):799-810. doi: 10.1089/jir.2005.25.799. J Interferon Cytokine Res. 2005. PMID: 16375608 Review.

8

Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin.

Panaretakis T, Hjortsberg L, Tamm KP, Björklund AC, Joseph B, Grandér D. Panaretakis T, et al. Mol Biol Cell. 2008 Jan;19(1):41-50. doi: 10.1091/mbc.e07-04-0358. Epub 2007 Oct 17. Mol Biol Cell. 2008. PMID: 17942603 Free PMC article.

9

Dexamethasone-induced apoptosis in acute lymphoblastic leukemia involves differential regulation of Bcl-2 family members.

Laane E, Panaretakis T, Pokrovskaja K, Buentke E, Corcoran M, Söderhäll S, Heyman M, Mazur J, Zhivotovsky B, Porwit A, Grandér D. Laane E, et al. Among authors: panaretakis t. Haematologica. 2007 Nov;92(11):1460-9. doi: 10.3324/haematol.10543. Haematologica. 2007. PMID: 18024393 Free article.

10

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy.

Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Oscarsson J, Corcoran M, Björklund AC, Hultenby K, Lundin J, Heyman M, Söderhäll S, Mazur J, Porwit A, Pandolfi PP, Zhivotovsky B, Panaretakis T, Grandér D. Laane E, et al. Among authors: panaretakis t. Cell Death Differ. 2009 Jul;16(7):1018-29. doi: 10.1038/cdd.2009.46. Epub 2009 Apr 24. Cell Death Differ. 2009. PMID: 19390558

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