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Page 1
PTEN mutations as a cause of constitutive insulin sensitivity and obesity.
Pal A, Barber TM, Van de Bunt M, Rudge SA, Zhang Q, Lachlan KL, Cooper NS, Linden H, Levy JC, Wakelam MJ, Walker L, Karpe F, Gloyn AL. Pal A, et al. Among authors: rudge sa. N Engl J Med. 2012 Sep 13;367(11):1002-11. doi: 10.1056/NEJMoa1113966. N Engl J Med. 2012. PMID: 22970944 Free PMC article.
Cross-talk between phospholipase D and MAP kinases activities.
Wakelam MJ, McNee GS, Rudge SA. Wakelam MJ, et al. Among authors: rudge sa. Adv Enzyme Regul. 2010;50(1):57-61. doi: 10.1016/j.advenzreg.2009.10.032. Epub 2009 Nov 5. Adv Enzyme Regul. 2010. PMID: 19896495 No abstract available.
SnapShot: lipid kinases and phosphatases.
Rudge SA, Wakelam MJ. Rudge SA, et al. Cell. 2013 Dec 19;155(7):1654-1654.e1. doi: 10.1016/j.cell.2013.12.005. Cell. 2013. PMID: 24360283 Free article. No abstract available.
Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations.
Huang-Doran I, Tomlinson P, Payne F, Gast A, Sleigh A, Bottomley W, Harris J, Daly A, Rocha N, Rudge S, Clark J, Kwok A, Romeo S, McCann E, Müksch B, Dattani M, Zucchini S, Wakelam M, Foukas LC, Savage DB, Murphy R, O'Rahilly S, Barroso I, Semple RK. Huang-Doran I, et al. JCI Insight. 2016 Oct 20;1(17):e88766. doi: 10.1172/jci.insight.88766. JCI Insight. 2016. PMID: 27766312 Free PMC article.
Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA.
Lindhurst MJ, Parker VE, Payne F, Sapp JC, Rudge S, Harris J, Witkowski AM, Zhang Q, Groeneveld MP, Scott CE, Daly A, Huson SM, Tosi LL, Cunningham ML, Darling TN, Geer J, Gucev Z, Sutton VR, Tziotzios C, Dixon AK, Helliwell T, O'Rahilly S, Savage DB, Wakelam MJ, Barroso I, Biesecker LG, Semple RK. Lindhurst MJ, et al. Nat Genet. 2012 Jun 24;44(8):928-33. doi: 10.1038/ng.2332. Nat Genet. 2012. PMID: 22729222 Free PMC article.
33 results