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Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII.
Wagschal A, Rousset E, Basavarajaiah P, Contreras X, Harwig A, Laurent-Chabalier S, Nakamura M, Chen X, Zhang K, Meziane O, Boyer F, Parrinello H, Berkhout B, Terzian C, Benkirane M, Kiernan R. Wagschal A, et al. Among authors: basavarajaiah p. Cell. 2012 Sep 14;150(6):1147-57. doi: 10.1016/j.cell.2012.08.004. Cell. 2012. PMID: 22980978 Free PMC article.
Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR.
Nakamura M, Basavarajaiah P, Rousset E, Beraud C, Latreille D, Henaoui IS, Lassot I, Mari B, Kiernan R. Nakamura M, et al. Among authors: basavarajaiah p. Retrovirology. 2012 Feb 8;9:13. doi: 10.1186/1742-4690-9-13. Retrovirology. 2012. PMID: 22316138 Free PMC article.
Chromatin-associated MRN complex protects highly transcribing genes from genomic instability.
Salifou K, Burnard C, Basavarajaiah P, Grasso G, Helsmoortel M, Mac V, Depierre D, Franckhauser C, Beyne E, Contreras X, Dejardin J, Rouquier S, Cuvier O, Kiernan R. Salifou K, et al. Among authors: basavarajaiah p. Sci Adv. 2021 May 21;7(21):eabb2947. doi: 10.1126/sciadv.abb2947. Print 2021 May. Sci Adv. 2021. PMID: 34020942 Free PMC article.