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Preparation and optimization of new 4-(morpholin-4-yl)-(6-oxo-1,6-dihydropyrimidin-2-yl)amide derivatives as PI3Kβ inhibitors.
Bioorg Med Chem Lett. 2012 Oct 15;22(20):6381-4. doi: 10.1016/j.bmcl.2012.08.072. Epub 2012 Aug 25.
Bioorg Med Chem Lett. 2012.
PMID: 22981333
Biphenyls as surrogates of the steroidal backbone. Part 2: discovery of a novel family of non-steroidal 5-alpha-reductase inhibitors.
Lesuisse D, Gourvest JF, Albert E, Doucet B, Hartmann C, Lefrançois JM, Tessier S, Tric B, Teutsch G.
Lesuisse D, et al. Among authors: tric b.
Bioorg Med Chem Lett. 2001 Jul 9;11(13):1713-6. doi: 10.1016/s0960-894x(01)00268-2.
Bioorg Med Chem Lett. 2001.
PMID: 11425544
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Biphenyls as surrogates of the steroidal backbone. Part 1: synthesis and estrogen receptor affinity of an original series of polysubstituted biphenyls.
Lesuisse D, Albert E, Bouchoux F, Cérède E, Lefrançois JM, Levif MO, Tessier S, Tric B, Teutsch G.
Lesuisse D, et al. Among authors: tric b.
Bioorg Med Chem Lett. 2001 Jul 9;11(13):1709-12. doi: 10.1016/s0960-894x(01)00267-0.
Bioorg Med Chem Lett. 2001.
PMID: 11425543
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Synthesis and evaluation of a new series of mechanism-based aromatase inhibitors.
Lesuisse D, Gourvest JF, Hartmann C, Tric B, Benslimane O, Philibert D, Vevert JP.
Lesuisse D, et al. Among authors: tric b.
J Med Chem. 1992 May 1;35(9):1588-97. doi: 10.1021/jm00087a013.
J Med Chem. 1992.
PMID: 1578485
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Structure-activity relationships of a new family of steroidal aromatase inhibitors. 1. Synthesis and evaluation of a series of analogs related to 19-[(methylthio)methyl]androstenedione (RU54115).
Lesuisse D, Gourvest JF, Benslimane O, Canu F, Delaisi C, Doucet B, Hartmann C, Lefrançois JM, Tric B, Mansuy D, Philibert D, Teutsch G.
Lesuisse D, et al. Among authors: tric b.
J Med Chem. 1996 Feb 2;39(3):757-72. doi: 10.1021/jm950539l.
J Med Chem. 1996.
PMID: 8576919
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RU54115, a tight-binding aromatase inhibitor potentially useful for the treatment of breast cancer.
Delaisi C, Doucet B, Hartmann C, Tric B, Gourvest JF, Lesuisse D.
Delaisi C, et al. Among authors: tric b.
J Steroid Biochem Mol Biol. 1992 Mar;41(3-8):773-7. doi: 10.1016/0960-0760(92)90422-f.
J Steroid Biochem Mol Biol. 1992.
PMID: 1562553
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