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Rare ADH variant constellations are specific for alcohol dependence.
Zuo L, Zhang H, Malison RT, Li CS, Zhang XY, Wang F, Lu L, Lu L, Wang X, Krystal JH, Zhang F, Deng HW, Luo X. Zuo L, et al. Among authors: deng hw. Alcohol Alcohol. 2013 Jan-Feb;48(1):9-14. doi: 10.1093/alcalc/ags104. Epub 2012 Sep 27. Alcohol Alcohol. 2013. PMID: 23019235 Free PMC article.
Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.
Zuo L, Gelernter J, Zhang CK, Zhao H, Lu L, Kranzler HR, Malison RT, Li CS, Wang F, Zhang XY, Deng HW, Krystal JH, Zhang F, Luo X. Zuo L, et al. Among authors: deng hw. Neuropsychopharmacology. 2012 Jan;37(2):557-66. doi: 10.1038/npp.2011.229. Epub 2011 Sep 28. Neuropsychopharmacology. 2012. PMID: 21956439 Free PMC article.
Genome-wide meta-analysis of alcohol use disorder in East Asians.
Zhou H, Kalayasiri R, Sun Y, Nuñez YZ, Deng HW, Chen XD, Justice AC, Kranzler HR, Chang S, Lu L, Shi J, Sanichwankul K, Mutirangura A, Malison RT, Gelernter J. Zhou H, et al. Among authors: deng hw. Neuropsychopharmacology. 2022 Sep;47(10):1791-1797. doi: 10.1038/s41386-022-01265-w. Epub 2022 Jan 29. Neuropsychopharmacology. 2022. PMID: 35094024 Free PMC article.
ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.
Quillen EE, Chen XD, Almasy L, Yang F, He H, Li X, Wang XY, Liu TQ, Hao W, Deng HW, Kranzler HR, Gelernter J. Quillen EE, et al. Among authors: deng hw. Am J Med Genet B Neuropsychiatr Genet. 2014 Mar;165B(2):103-10. doi: 10.1002/ajmg.b.32213. Epub 2013 Nov 26. Am J Med Genet B Neuropsychiatr Genet. 2014. PMID: 24277619 Free PMC article.
759 results