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Neuropeptide Y (NPY): genetic variation in the human promoter alters glucocorticoid signaling, yielding increased NPY secretion and stress responses.
Zhang K, Rao F, Miramontes-Gonzalez JP, Hightower CM, Vaught B, Chen Y, Greenwood TA, Schork AJ, Wang L, Mahata M, Stridsberg M, Khandrika S, Biswas N, Fung MM, Waalen J, Middelberg RP, Heath AC, Montgomery GW, Martin NG, Whitfield JB, Baker DG, Schork NJ, Nievergelt CM, O'Connor DT. Zhang K, et al. Among authors: rao f. J Am Coll Cardiol. 2012 Oct 23;60(17):1678-89. doi: 10.1016/j.jacc.2012.06.042. Epub 2012 Sep 26. J Am Coll Cardiol. 2012. PMID: 23021333 Free PMC article.
Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion.
Chen Y, Rao F, Rodriguez-Flores JL, Mahata M, Fung MM, Stridsberg M, Vaingankar SM, Wen G, Salem RM, Das M, Cockburn MG, Schork NJ, Ziegler MG, Hamilton BA, Mahata SK, Taupenot L, O'Connor DT. Chen Y, et al. Among authors: rao f. J Am Coll Cardiol. 2008 Oct 28;52(18):1468-81. doi: 10.1016/j.jacc.2008.07.047. J Am Coll Cardiol. 2008. PMID: 19017515 Free PMC article.
Neuropeptide Y(1) Receptor NPY1R discovery of naturally occurring human genetic variants governing gene expression in cella as well as pleiotropic effects on autonomic activity and blood pressure in vivo.
Wang L, Rao F, Zhang K, Mahata M, Rodriguez-Flores JL, Fung MM, Waalen J, Cockburn MG, Hamilton BA, Mahata SK, O'Connor DT. Wang L, et al. Among authors: rao f. J Am Coll Cardiol. 2009 Sep 1;54(10):944-54. doi: 10.1016/j.jacc.2009.05.035. J Am Coll Cardiol. 2009. PMID: 19712806 Free PMC article.
Peptide YY (PYY) gene polymorphisms in the 3'-untranslated and proximal promoter regions regulate cellular gene expression and PYY secretion and metabolic syndrome traits in vivo.
Shih PA, Wang L, Chiron S, Wen G, Nievergelt C, Mahata M, Khandrika S, Rao F, Fung MM, Mahata SK, Hamilton BA, O'Connor DT. Shih PA, et al. Among authors: rao f. J Clin Endocrinol Metab. 2009 Nov;94(11):4557-66. doi: 10.1210/jc.2009-0465. Epub 2009 Oct 9. J Clin Endocrinol Metab. 2009. PMID: 19820027 Free PMC article.
Genetic variation within a metabolic motif in the chromogranin a promoter: pleiotropic influence on cardiometabolic risk traits in twins.
Rao F, Chiron S, Wei Z, Fung MM, Chen Y, Wen G, Khandrika S, Ziegler MG, Benyamin B, Montgomery G, Whitfield JB, Martin NG, Waalen J, Hamilton BA, Mahata SK, O'Connor DT. Rao F, et al. Am J Hypertens. 2012 Jan;25(1):29-40. doi: 10.1038/ajh.2011.163. Epub 2011 Sep 15. Am J Hypertens. 2012. PMID: 21918574 Free PMC article.
Heredity and cardiometabolic risk: naturally occurring polymorphisms in the human neuropeptide Y(2) receptor promoter disrupt multiple transcriptional response motifs.
Wei Z, Zhang K, Wen G, Balasubramanian K, Shih PA, Rao F, Friese RS, Miramontes-Gonzalez JP, Schmid-Schoenbein GW, Kim HS, Mahata SK, O'Connor DT. Wei Z, et al. Among authors: rao f. J Hypertens. 2013 Jan;31(1):123-33. doi: 10.1097/HJH.0b013e32835b053d. J Hypertens. 2013. PMID: 23149563 Free PMC article.
408 results