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Neuropeptide Y (NPY): genetic variation in the human promoter alters glucocorticoid signaling, yielding increased NPY secretion and stress responses.
Zhang K, Rao F, Miramontes-Gonzalez JP, Hightower CM, Vaught B, Chen Y, Greenwood TA, Schork AJ, Wang L, Mahata M, Stridsberg M, Khandrika S, Biswas N, Fung MM, Waalen J, Middelberg RP, Heath AC, Montgomery GW, Martin NG, Whitfield JB, Baker DG, Schork NJ, Nievergelt CM, O'Connor DT. Zhang K, et al. J Am Coll Cardiol. 2012 Oct 23;60(17):1678-89. doi: 10.1016/j.jacc.2012.06.042. Epub 2012 Sep 26. J Am Coll Cardiol. 2012. PMID: 23021333 Free PMC article.
Neuropeptide Y(1) Receptor NPY1R discovery of naturally occurring human genetic variants governing gene expression in cella as well as pleiotropic effects on autonomic activity and blood pressure in vivo.
Wang L, Rao F, Zhang K, Mahata M, Rodriguez-Flores JL, Fung MM, Waalen J, Cockburn MG, Hamilton BA, Mahata SK, O'Connor DT. Wang L, et al. Among authors: zhang k. J Am Coll Cardiol. 2009 Sep 1;54(10):944-54. doi: 10.1016/j.jacc.2009.05.035. J Am Coll Cardiol. 2009. PMID: 19712806 Free PMC article.
Heredity and cardiometabolic risk: naturally occurring polymorphisms in the human neuropeptide Y(2) receptor promoter disrupt multiple transcriptional response motifs.
Wei Z, Zhang K, Wen G, Balasubramanian K, Shih PA, Rao F, Friese RS, Miramontes-Gonzalez JP, Schmid-Schoenbein GW, Kim HS, Mahata SK, O'Connor DT. Wei Z, et al. Among authors: zhang k. J Hypertens. 2013 Jan;31(1):123-33. doi: 10.1097/HJH.0b013e32835b053d. J Hypertens. 2013. PMID: 23149563 Free PMC article.
Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected].
Zhang K, Deacon DC, Rao F, Schork AJ, Fung MM, Waalen J, Schork NJ, Nievergelt CM, Chi NC, O'Connor DT. Zhang K, et al. J Am Coll Cardiol. 2014 Feb 4;63(4):358-68. doi: 10.1016/j.jacc.2013.09.025. Epub 2013 Oct 16. J Am Coll Cardiol. 2014. PMID: 24140660 Free PMC article.
Genetic implication of a novel thiamine transporter in human hypertension.
Zhang K, Huentelman MJ, Rao F, Sun EI, Corneveaux JJ, Schork AJ, Wei Z, Waalen J, Miramontes-Gonzalez JP, Hightower CM, Maihofer AX, Mahata M, Pastinen T, Ehret GB; International Consortium for Blood Pressure Genome-Wide Association Studies; Schork NJ, Eskin E, Nievergelt CM, Saier MH Jr, O'Connor DT. Zhang K, et al. J Am Coll Cardiol. 2014 Apr 22;63(15):1542-55. doi: 10.1016/j.jacc.2014.01.007. Epub 2014 Feb 5. J Am Coll Cardiol. 2014. PMID: 24509276 Free PMC article.
Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo.
Rao F, Zhang L, Wessel J, Zhang K, Wen G, Kennedy BP, Rana BK, Das M, Rodriguez-Flores JL, Smith DW, Cadman PE, Salem RM, Mahata SK, Schork NJ, Taupenot L, Ziegler MG, O'Connor DT. Rao F, et al. Among authors: zhang l, zhang k. Circulation. 2007 Aug 28;116(9):993-1006. doi: 10.1161/CIRCULATIONAHA.106.682302. Epub 2007 Aug 13. Circulation. 2007. PMID: 17698732
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