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Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.
Ramasamy A, Kuokkanen M, Vedantam S, Gajdos ZK, Couto Alves A, Lyon HN, Ferreira MA, Strachan DP, Zhao JH, Abramson MJ, Brown MA, Coin L, Dharmage SC, Duffy DL, Haahtela T, Heath AC, Janson C, Kähönen M, Khaw KT, Laitinen J, Le Souef P, Lehtimäki T; Australian Asthma Genetics Consortium Collaborators; Madden PA, Marks GB, Martin NG, Matheson MC, Palmer CD, Palotie A, Pouta A, Robertson CF, Viikari J, Widen E, Wjst M, Jarvis DL, Montgomery GW, Thompson PJ, Wareham N, Eriksson J, Jousilahti P, Laitinen T, Pekkanen J, Raitakari OT, O'Connor GT, Salomaa V, Jarvelin MR, Hirschhorn JN. Ramasamy A, et al. Among authors: haahtela t. PLoS One. 2012;7(9):e44008. doi: 10.1371/journal.pone.0044008. Epub 2012 Sep 28. PLoS One. 2012. PMID: 23028483 Free PMC article.
A large-scale, consortium-based genomewide association study of asthma.
Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WOCM; GABRIEL Consortium. Moffatt MF, et al. N Engl J Med. 2010 Sep 23;363(13):1211-1221. doi: 10.1056/NEJMoa0906312. N Engl J Med. 2010. PMID: 20860503 Free PMC article.
Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.
Ferreira MA, Matheson MC, Duffy DL, Marks GB, Hui J, Le Souëf P, Danoy P, Baltic S, Nyholt DR, Jenkins M, Hayden C, Willemsen G, Ang W, Kuokkanen M, Beilby J, Cheah F, de Geus EJ, Ramasamy A, Vedantam S, Salomaa V, Madden PA, Heath AC, Hopper JL, Visscher PM, Musk B, Leeder SR, Jarvelin MR, Pennell C, Boomsma DI, Hirschhorn JN, Walters H, Martin NG, James A, Jones G, Abramson MJ, Robertson CF, Dharmage SC, Brown MA, Montgomery GW, Thompson PJ; Australian Asthma Genetics Consortium. Ferreira MA, et al. Lancet. 2011 Sep 10;378(9795):1006-14. doi: 10.1016/S0140-6736(11)60874-X. Lancet. 2011. PMID: 21907864 Free PMC article.
The relation of airway obstruction to asthma, chronic rhinosinusitis and age: results from a population survey of adults.
Obaseki D, Potts J, Joos G, Baelum J, Haahtela T, Ahlström M, Matricardi P, Kramer U, Gjomarkaj M, Fokkens W, Makowska J, Todo-Bom A, Toren K, Janson C, Dahlen SE, Forsberg B, Jarvis D, Howarth P, Brozek G, Minov J, Bachert C, Burney P; GA2LEN network of excellence. Obaseki D, et al. Among authors: haahtela t. Allergy. 2014 Sep;69(9):1205-14. doi: 10.1111/all.12447. Epub 2014 Jul 19. Allergy. 2014. PMID: 24841074 Free PMC article.
Hunt for the origin of allergy - comparing the Finnish and Russian Karelia.
Haahtela T, Laatikainen T, Alenius H, Auvinen P, Fyhrquist N, Hanski I, von Hertzen L, Jousilahti P, Kosunen TU, Markelova O, Mäkelä MJ, Pantelejev V, Uhanov M, Zilber E, Vartiainen E. Haahtela T, et al. Clin Exp Allergy. 2015 May;45(5):891-901. doi: 10.1111/cea.12527. Clin Exp Allergy. 2015. PMID: 25772429
539 results