Maloney DJ - Search Results

1

High-throughput 1,536-well fluorescence polarization assays for α(1)-acid glycoprotein and human serum albumin binding.

Yasgar A, Furdas SD, Maloney DJ, Jadhav A, Jung M, Simeonov A. Yasgar A, et al. Among authors: maloney dj. PLoS One. 2012;7(9):e45594. doi: 10.1371/journal.pone.0045594. Epub 2012 Sep 20. PLoS One. 2012. PMID: 23029124 Free PMC article.

2

A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2.

Jameson JB 2nd, Kantz A, Schultz L, Kalyanaraman C, Jacobson MP, Maloney DJ, Jadhav A, Simeonov A, Holman TR. Jameson JB 2nd, et al. Among authors: maloney dj. PLoS One. 2014 Aug 11;9(8):e104094. doi: 10.1371/journal.pone.0104094. eCollection 2014. PLoS One. 2014. PMID: 25111178 Free PMC article.

3

High-throughput identification of promiscuous inhibitors from screening libraries with the use of a thiol-containing fluorescent probe.

McCallum MM, Nandhikonda P, Temmer JJ, Eyermann C, Simeonov A, Jadhav A, Yasgar A, Maloney D, Arnold AL. McCallum MM, et al. J Biomol Screen. 2013 Jul;18(6):705-13. doi: 10.1177/1087057113476090. Epub 2013 Feb 27. J Biomol Screen. 2013. PMID: 23446699 Free PMC article.

4

Inhibition of DNA glycosylases via small molecule purine analogs.

Jacobs AC, Calkins MJ, Jadhav A, Dorjsuren D, Maloney D, Simeonov A, Jaruga P, Dizdaroglu M, McCullough AK, Lloyd RS. Jacobs AC, et al. PLoS One. 2013 Dec 9;8(12):e81667. doi: 10.1371/journal.pone.0081667. eCollection 2013. PLoS One. 2013. PMID: 24349107 Free PMC article.

5

The pilot phase of the NIH Chemical Genomics Center.

Thomas CJ, Auld DS, Huang R, Huang W, Jadhav A, Johnson RL, Leister W, Maloney DJ, Marugan JJ, Michael S, Simeonov A, Southall N, Xia M, Zheng W, Inglese J, Austin CP. Thomas CJ, et al. Among authors: maloney dj. Curr Top Med Chem. 2009;9(13):1181-93. doi: 10.2174/156802609789753644. Curr Top Med Chem. 2009. PMID: 19807664 Free PMC article. Review.

6

Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease.

Jadhav A, Ferreira RS, Klumpp C, Mott BT, Austin CP, Inglese J, Thomas CJ, Maloney DJ, Shoichet BK, Simeonov A. Jadhav A, et al. Among authors: maloney dj. J Med Chem. 2010 Jan 14;53(1):37-51. doi: 10.1021/jm901070c. J Med Chem. 2010. PMID: 19908840 Free PMC article.

7

Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity.

Dorjsuren D, Kim D, Maloney DJ, Wilson DM 3rd, Simeonov A. Dorjsuren D, et al. Among authors: maloney dj. Nucleic Acids Res. 2011 Jan;39(2):e11. doi: 10.1093/nar/gkq1082. Epub 2010 Nov 9. Nucleic Acids Res. 2011. PMID: 21062821 Free PMC article.

8

Diverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collection.

Dorjsuren D, Kim D, Vyjayanti VN, Maloney DJ, Jadhav A, Wilson DM 3rd, Simeonov A. Dorjsuren D, et al. Among authors: maloney dj. PLoS One. 2012;7(10):e47974. doi: 10.1371/journal.pone.0047974. Epub 2012 Oct 23. PLoS One. 2012. PMID: 23110144 Free PMC article.

9

High-throughput screen identifies cyclic nucleotide analogs that inhibit prostatic acid phosphatase.

McCoy ES, Lea WA, Mott BT, Maloney DJ, Jadhav A, Simeonov A, Zylka MJ. McCoy ES, et al. Among authors: maloney dj. J Biomol Screen. 2013 Apr;18(4):481-9. doi: 10.1177/1087057112468613. Epub 2012 Nov 27. J Biomol Screen. 2013. PMID: 23190738 Free PMC article.

10

A fluorescence-based high throughput assay for the determination of small molecule-human serum albumin protein binding.

McCallum MM, Pawlak AJ, Shadrick WR, Simeonov A, Jadhav A, Yasgar A, Maloney DJ, Arnold LA. McCallum MM, et al. Among authors: maloney dj. Anal Bioanal Chem. 2014 Mar;406(7):1867-75. doi: 10.1007/s00216-013-7560-3. Epub 2014 Jan 5. Anal Bioanal Chem. 2014. PMID: 24390461 Free PMC article.

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