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Hematopoietic G-protein-coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor-knockout mice.
Otten JJ, de Jager SC, Kavelaars A, Seijkens T, Bot I, Wijnands E, Beckers L, Westra MM, Bot M, Busch M, Bermudez B, van Berkel TJ, Heijnen CJ, Biessen EA. Otten JJ, et al. Among authors: seijkens t. FASEB J. 2013 Jan;27(1):265-76. doi: 10.1096/fj.12-205351. Epub 2012 Oct 9. FASEB J. 2013. PMID: 23047899 Free PMC article.
Diet-induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow.
van den Berg SM, Seijkens TT, Kusters PJ, Beckers L, den Toom M, Smeets E, Levels J, de Winther MP, Lutgens E. van den Berg SM, et al. Among authors: seijkens tt. FASEB J. 2016 May;30(5):1779-88. doi: 10.1096/fj.201500175. Epub 2016 Jan 26. FASEB J. 2016. PMID: 26813974
This implies that the effects of obesity on HSPCs hampers proper functioning of the immune system.-Van den Berg, S. M., Seijkens, T. T. P., Kusters, P. J. H., Beckers, L., den Toom, M., Smeets, E., Levels, J., de Winther, M. ...
This implies that the effects of obesity on HSPCs hampers proper functioning of the immune system.-Van den Berg, S. M., Seijkens, …
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile.
Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, Seijkens T, Engel D, Cleutjens J, Keller AM, Naik SH, Boon L, Oufella HA, Mallat Z, Ahonen CL, Noelle RJ, de Winther MP, Daemen MJ, Biessen EA, Weber C. Lutgens E, et al. Among authors: seijkens t. J Exp Med. 2010 Feb 15;207(2):391-404. doi: 10.1084/jem.20091293. Epub 2010 Jan 25. J Exp Med. 2010. PMID: 20100871 Free PMC article.
Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis.
Lievens D, Zernecke A, Seijkens T, Soehnlein O, Beckers L, Munnix IC, Wijnands E, Goossens P, van Kruchten R, Thevissen L, Boon L, Flavell RA, Noelle RJ, Gerdes N, Biessen EA, Daemen MJ, Heemskerk JW, Weber C, Lutgens E. Lievens D, et al. Among authors: seijkens t. Blood. 2010 Nov 18;116(20):4317-27. doi: 10.1182/blood-2010-01-261206. Epub 2010 Aug 12. Blood. 2010. PMID: 20705757 Free PMC article.
Constitutive CD40 Signaling in Dendritic Cells Limits Atherosclerosis by Provoking Inflammatory Bowel Disease and Ensuing Cholesterol Malabsorption.
Kusters P, Seijkens T, Bürger C, Legein B, Winkels H, Gijbels M, Barthels C, Bennett R, Beckers L, Atzler D, Biessen E, Brocker T, Weber C, Gerdes N, Lutgens E. Kusters P, et al. Among authors: seijkens t. Am J Pathol. 2017 Dec;187(12):2912-2919. doi: 10.1016/j.ajpath.2017.08.016. Epub 2017 Sep 19. Am J Pathol. 2017. PMID: 28935569 Free article.
The immunobiology of CD154-CD40-TRAF interactions in atherosclerosis.
Engel D, Seijkens T, Poggi M, Sanati M, Thevissen L, Beckers L, Wijnands E, Lievens D, Lutgens E. Engel D, et al. Among authors: seijkens t. Semin Immunol. 2009 Oct;21(5):308-12. doi: 10.1016/j.smim.2009.06.004. Epub 2009 Jul 17. Semin Immunol. 2009. PMID: 19616449 Review.
Plasmacytoid dendritic cells protect against atherosclerosis by tuning T-cell proliferation and activity.
Daissormont IT, Christ A, Temmerman L, Sampedro Millares S, Seijkens T, Manca M, Rousch M, Poggi M, Boon L, van der Loos C, Daemen M, Lutgens E, Halvorsen B, Aukrust P, Janssen E, Biessen EA. Daissormont IT, et al. Among authors: seijkens t. Circ Res. 2011 Dec 9;109(12):1387-95. doi: 10.1161/CIRCRESAHA.111.256529. Epub 2011 Oct 20. Circ Res. 2011. PMID: 22021930 Free PMC article.
51 results