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Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases.
Kodack DP, Chung E, Yamashita H, Incio J, Duyverman AM, Song Y, Farrar CT, Huang Y, Ager E, Kamoun W, Goel S, Snuderl M, Lussiez A, Hiddingh L, Mahmood S, Tannous BA, Eichler AF, Fukumura D, Engelman JA, Jain RK. Kodack DP, et al. Among authors: duyverman am. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):E3119-27. doi: 10.1073/pnas.1216078109. Epub 2012 Oct 15. Proc Natl Acad Sci U S A. 2012. PMID: 23071298 Free PMC article.
Malignant cells facilitate lung metastasis by bringing their own soil.
Duda DG, Duyverman AM, Kohno M, Snuderl M, Steller EJ, Fukumura D, Jain RK. Duda DG, et al. Among authors: duyverman am. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21677-82. doi: 10.1073/pnas.1016234107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098274 Free PMC article.
An isolated tumor perfusion model in mice.
Duyverman AM, Kohno M, Roberge S, Fukumura D, Duda DG, Jain RK. Duyverman AM, et al. Nat Protoc. 2012 Mar 22;7(4):749-55. doi: 10.1038/nprot.2012.030. Nat Protoc. 2012. PMID: 22441293 Free PMC article.
Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors.
Chen Y, Liu YC, Sung YC, Ramjiawan RR, Lin TT, Chang CC, Jeng KS, Chang CF, Liu CH, Gao DY, Hsu FF, Duyverman AM, Kitahara S, Huang P, Dima S, Popescu I, Flaherty KT, Zhu AX, Bardeesy N, Jain RK, Benes CH, Duda DG. Chen Y, et al. Among authors: duyverman am. Sci Rep. 2017 Mar 9;7:44123. doi: 10.1038/srep44123. Sci Rep. 2017. PMID: 28276530 Free PMC article.
Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice.
Chen Y, Huang Y, Reiberger T, Duyverman AM, Huang P, Samuel R, Hiddingh L, Roberge S, Koppel C, Lauwers GY, Zhu AX, Jain RK, Duda DG. Chen Y, et al. Among authors: duyverman am. Hepatology. 2014 Apr;59(4):1435-47. doi: 10.1002/hep.26790. Epub 2014 Feb 18. Hepatology. 2014. PMID: 24242874 Free PMC article.
Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice.
Kamoun WS, Ley CD, Farrar CT, Duyverman AM, Lahdenranta J, Lacorre DA, Batchelor TT, di Tomaso E, Duda DG, Munn LL, Fukumura D, Sorensen AG, Jain RK. Kamoun WS, et al. Among authors: duyverman am. J Clin Oncol. 2009 May 20;27(15):2542-52. doi: 10.1200/JCO.2008.19.9356. Epub 2009 Mar 30. J Clin Oncol. 2009. PMID: 19332720 Free PMC article.