Woerle HJ - Search Results

1

Pharmacokinetics of single and multiple oral doses of 5 mg linagliptin in healthy Chinese volunteers.

Friedrich C, Shi X, Zeng P, Ring A, Woerle HJ, Patel S. Friedrich C, et al. Among authors: woerle hj. Int J Clin Pharmacol Ther. 2012 Dec;50(12):889-95. doi: 10.5414/CP201802. Int J Clin Pharmacol Ther. 2012. PMID: 23073142 Clinical Trial.

2

A randomized, open-label, crossover study to evaluate the pharmacokinetics of empagliflozin and linagliptin after coadministration in healthy male volunteers.

Friedrich C, Metzmann K, Rose P, Mattheus M, Pinnetti S, Woerle HJ. Friedrich C, et al. Among authors: woerle hj. Clin Ther. 2013 Jan;35(1):A33-42. doi: 10.1016/j.clinthera.2012.12.002. Clin Ther. 2013. PMID: 23328275 Clinical Trial.

3

Evaluation of the pharmacokinetic interaction between the dipeptidyl peptidase-4 inhibitor linagliptin and pioglitazone in healthy volunteers.

Graefe-Mody EU, Jungnik A, Ring A, Woerle HJ, Dugi KA. Graefe-Mody EU, et al. Among authors: woerle hj. Int J Clin Pharmacol Ther. 2010 Oct;48(10):652-61. doi: 10.5414/cpp48652. Int J Clin Pharmacol Ther. 2010. PMID: 20875371 Clinical Trial.

4

Assessment of the pharmacokinetic interaction between the novel DPP-4 inhibitor linagliptin and a sulfonylurea, glyburide, in healthy subjects.

Graefe-Mody U, Rose P, Ring A, Zander K, Iovino M, Woerle HJ. Graefe-Mody U, et al. Among authors: woerle hj. Drug Metab Pharmacokinet. 2011;26(2):123-9. doi: 10.2133/dmpk.dmpk-10-rg-091. Epub 2010 Nov 12. Drug Metab Pharmacokinet. 2011. PMID: 21084763 Free article. Clinical Trial.

5

Effect of multiple oral doses of linagliptin on the steady-state pharmacokinetics of a combination oral contraceptive in healthy female adults: an open-label, two-period, fixed-sequence, multiple-dose study.

Friedrich C, Port A, Ring A, Graefe-Mody U, Giessmann T, Iovino M, Woerle HJ. Friedrich C, et al. Among authors: woerle hj. Clin Drug Investig. 2011;31(9):643-53. doi: 10.2165/11590240-000000000-00000. Clin Drug Investig. 2011. PMID: 21714581 Clinical Trial.

6

A randomized, open-label, crossover study evaluating the effect of food on the relative bioavailability of linagliptin in healthy subjects.

Graefe-Mody U, Giessmann T, Ring A, Iovino M, Woerle HJ. Graefe-Mody U, et al. Among authors: woerle hj. Clin Ther. 2011 Aug;33(8):1096-103. doi: 10.1016/j.clinthera.2011.07.005. Epub 2011 Jul 30. Clin Ther. 2011. PMID: 21803422 Clinical Trial.

7

Pharmacokinetics of linagliptin in subjects with hepatic impairment.

Graefe-Mody U, Rose P, Retlich S, Ring A, Waldhauser L, Cinca R, Woerle HJ. Graefe-Mody U, et al. Among authors: woerle hj. Br J Clin Pharmacol. 2012 Jul;74(1):75-85. doi: 10.1111/j.1365-2125.2012.04173.x. Br J Clin Pharmacol. 2012. PMID: 22242621 Free PMC article.

8

Pharmacokinetic and pharmacodynamic evaluation of linagliptin in African American patients with type 2 diabetes mellitus.

Friedrich C, Glund S, Lionetti D, Kissling CJ, Righetti J, Patel S, Graefe-Mody U, Retlich S, Woerle HJ. Friedrich C, et al. Among authors: woerle hj. Br J Clin Pharmacol. 2013 Sep;76(3):445-54. doi: 10.1111/bcp.12077. Br J Clin Pharmacol. 2013. PMID: 23331248 Free PMC article. Clinical Trial.

9

Renal impairment has no clinically relevant effect on the long-term exposure of linagliptin in patients with type 2 diabetes.

Friedrich C, Emser A, Woerle HJ, Graefe-Mody U. Friedrich C, et al. Among authors: woerle hj. Am J Ther. 2013 Nov-Dec;20(6):618-21. doi: 10.1097/MJT.0b013e31826232dc. Am J Ther. 2013. PMID: 23411609

10

Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin.

DeFronzo RA, Lewin A, Patel S, Liu D, Kaste R, Woerle HJ, Broedl UC. DeFronzo RA, et al. Among authors: woerle hj. Diabetes Care. 2015 Mar;38(3):384-93. doi: 10.2337/dc14-2364. Epub 2015 Jan 12. Diabetes Care. 2015. PMID: 25583754 Clinical Trial.

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