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Insights into the mechanism of cell death induced by saporin delivered into cancer cells by an antibody fusion protein targeting the transferrin receptor 1.
Daniels-Wells TR, Helguera G, Rodríguez JA, Leoh LS, Erb MA, Diamante G, Casero D, Pellegrini M, Martínez-Maza O, Penichet ML. Daniels-Wells TR, et al. Among authors: erb ma. Toxicol In Vitro. 2013 Feb;27(1):220-31. doi: 10.1016/j.tiv.2012.10.006. Epub 2012 Oct 17. Toxicol In Vitro. 2013. PMID: 23085102 Free PMC article.
Cell-Based Ligand Discovery for the ENL YEATS Domain.
Asiaban JN, Milosevich N, Chen E, Bishop TR, Wang J, Zhang Y, Ackerman CJ, Hampton EN, Young TS, Hull MV, Cravatt BF, Erb MA. Asiaban JN, et al. Among authors: erb ma. ACS Chem Biol. 2020 Apr 17;15(4):895-903. doi: 10.1021/acschembio.0c00124. Epub 2020 Mar 19. ACS Chem Biol. 2020. PMID: 32176478 Free PMC article.
Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia.
Garnar-Wortzel L, Bishop TR, Kitamura S, Milosevich N, Asiaban JN, Zhang X, Zheng Q, Chen E, Ramos AR, Ackerman CJ, Hampton EN, Chatterjee AK, Young TS, Hull MV, Sharpless KB, Cravatt BF, Wolan DW, Erb MA. Garnar-Wortzel L, et al. Among authors: erb ma. ACS Cent Sci. 2021 May 26;7(5):815-830. doi: 10.1021/acscentsci.0c01550. Epub 2021 Apr 30. ACS Cent Sci. 2021. PMID: 34079898 Free PMC article.
A short ORF-encoded transcriptional regulator.
Koh M, Ahmad I, Ko Y, Zhang Y, Martinez TF, Diedrich JK, Chu Q, Moresco JJ, Erb MA, Saghatelian A, Schultz PG, Bollong MJ. Koh M, et al. Among authors: erb ma. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2021943118. doi: 10.1073/pnas.2021943118. Proc Natl Acad Sci U S A. 2021. PMID: 33468658 Free PMC article.
Processing for destruction.
Erb MA. Erb MA. Nat Chem Biol. 2020 Jan;16(1):3-4. doi: 10.1038/s41589-019-0428-x. Nat Chem Biol. 2020. PMID: 31819275 No abstract available.
BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.
Winter GE, Mayer A, Buckley DL, Erb MA, Roderick JE, Vittori S, Reyes JM, di Iulio J, Souza A, Ott CJ, Roberts JM, Zeid R, Scott TG, Paulk J, Lachance K, Olson CM, Dastjerdi S, Bauer S, Lin CY, Gray NS, Kelliher MA, Churchman LS, Bradner JE. Winter GE, et al. Among authors: erb ma. Mol Cell. 2017 Jul 6;67(1):5-18.e19. doi: 10.1016/j.molcel.2017.06.004. Epub 2017 Jun 29. Mol Cell. 2017. PMID: 28673542 Free PMC article.
Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation.
Olson CM, Jiang B, Erb MA, Liang Y, Doctor ZM, Zhang Z, Zhang T, Kwiatkowski N, Boukhali M, Green JL, Haas W, Nomanbhoy T, Fischer ES, Young RA, Bradner JE, Winter GE, Gray NS. Olson CM, et al. Among authors: erb ma. Nat Chem Biol. 2018 Feb;14(2):163-170. doi: 10.1038/nchembio.2538. Epub 2017 Dec 18. Nat Chem Biol. 2018. PMID: 29251720 Free PMC article.
Transcription control by the ENL YEATS domain in acute leukaemia.
Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, Dhe-Paganon S, Zhang F, Orkin SH, Winter GE, Bradner JE. Erb MA, et al. Nature. 2017 Mar 9;543(7644):270-274. doi: 10.1038/nature21688. Epub 2017 Mar 1. Nature. 2017. PMID: 28241139 Free PMC article.
22 results