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N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.
Yu X, Zech T, McDonald L, Gonzalez EG, Li A, Macpherson I, Schwarz JP, Spence H, Futó K, Timpson P, Nixon C, Ma Y, Anton IM, Visegrády B, Insall RH, Oien K, Blyth K, Norman JC, Machesky LM. Yu X, et al. Among authors: nixon c. J Cell Biol. 2012 Oct 29;199(3):527-44. doi: 10.1083/jcb.201203025. Epub 2012 Oct 22. J Cell Biol. 2012. PMID: 23091069 Free PMC article.
LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest.
Morton JP, Jamieson NB, Karim SA, Athineos D, Ridgway RA, Nixon C, McKay CJ, Carter R, Brunton VG, Frame MC, Ashworth A, Oien KA, Evans TR, Sansom OJ. Morton JP, et al. Among authors: nixon c. Gastroenterology. 2010 Aug;139(2):586-97, 597.e1-6. doi: 10.1053/j.gastro.2010.04.055. Epub 2010 May 6. Gastroenterology. 2010. PMID: 20452353 Free PMC article.
ERK5 signalling in prostate cancer promotes an invasive phenotype.
Ramsay AK, McCracken SR, Soofi M, Fleming J, Yu AX, Ahmad I, Morland R, Machesky L, Nixon C, Edwards DR, Nuttall RK, Seywright M, Marquez R, Keller E, Leung HY. Ramsay AK, et al. Among authors: nixon c. Br J Cancer. 2011 Feb 15;104(4):664-72. doi: 10.1038/sj.bjc.6606062. Epub 2011 Jan 25. Br J Cancer. 2011. PMID: 21266977 Free PMC article.
Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression.
Dozynkiewicz MA, Jamieson NB, Macpherson I, Grindlay J, van den Berghe PV, von Thun A, Morton JP, Gourley C, Timpson P, Nixon C, McKay CJ, Carter R, Strachan D, Anderson K, Sansom OJ, Caswell PT, Norman JC. Dozynkiewicz MA, et al. Among authors: nixon c. Dev Cell. 2012 Jan 17;22(1):131-45. doi: 10.1016/j.devcel.2011.11.008. Epub 2011 Dec 22. Dev Cell. 2012. PMID: 22197222 Free PMC article.
Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion.
Muller PA, Trinidad AG, Timpson P, Morton JP, Zanivan S, van den Berghe PV, Nixon C, Karim SA, Caswell PT, Noll JE, Coffill CR, Lane DP, Sansom OJ, Neilsen PM, Norman JC, Vousden KH. Muller PA, et al. Among authors: nixon c. Oncogene. 2013 Mar 7;32(10):1252-65. doi: 10.1038/onc.2012.148. Epub 2012 May 14. Oncogene. 2013. PMID: 22580601 Free PMC article.
TIGAR is required for efficient intestinal regeneration and tumorigenesis.
Cheung EC, Athineos D, Lee P, Ridgway RA, Lambie W, Nixon C, Strathdee D, Blyth K, Sansom OJ, Vousden KH. Cheung EC, et al. Among authors: nixon c. Dev Cell. 2013 Jun 10;25(5):463-77. doi: 10.1016/j.devcel.2013.05.001. Epub 2013 May 30. Dev Cell. 2013. PMID: 23726973 Free PMC article.
Expression of KOC, S100P, mesothelin and MUC1 in pancreatico-biliary adenocarcinomas: development and utility of a potential diagnostic immunohistochemistry panel.
Ali A, Brown V, Denley S, Jamieson NB, Morton JP, Nixon C, Graham JS, Sansom OJ, Carter CR, McKay CJ, Duthie FR, Oien KA. Ali A, et al. Among authors: nixon c. BMC Clin Pathol. 2014 Jul 23;14:35. doi: 10.1186/1472-6890-14-35. eCollection 2014. BMC Clin Pathol. 2014. PMID: 25071419 Free PMC article.
Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest.
Dikovskaya D, Cole JJ, Mason SM, Nixon C, Karim SA, McGarry L, Clark W, Hewitt RN, Sammons MA, Zhu J, Athineos D, Leach JD, Marchesi F, van Tuyn J, Tait SW, Brock C, Morton JP, Wu H, Berger SL, Blyth K, Adams PD. Dikovskaya D, et al. Among authors: nixon c. Cell Rep. 2015 Sep 1;12(9):1483-96. doi: 10.1016/j.celrep.2015.07.055. Epub 2015 Aug 20. Cell Rep. 2015. PMID: 26299965 Free PMC article.
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Cardaci S, Zheng L, MacKay G, van den Broek NJ, MacKenzie ED, Nixon C, Stevenson D, Tumanov S, Bulusu V, Kamphorst JJ, Vazquez A, Fleming S, Schiavi F, Kalna G, Blyth K, Strathdee D, Gottlieb E. Cardaci S, et al. Among authors: nixon c. Nat Cell Biol. 2015 Oct;17(10):1317-26. doi: 10.1038/ncb3233. Epub 2015 Aug 24. Nat Cell Biol. 2015. PMID: 26302408 Free PMC article.
412 results