Spence H - Search Results

1

N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.

Yu X, Zech T, McDonald L, Gonzalez EG, Li A, Macpherson I, Schwarz JP, Spence H, Futó K, Timpson P, Nixon C, Ma Y, Anton IM, Visegrády B, Insall RH, Oien K, Blyth K, Norman JC, Machesky LM. Yu X, et al. Among authors: spence h. J Cell Biol. 2012 Oct 29;199(3):527-44. doi: 10.1083/jcb.201203025. Epub 2012 Oct 22. J Cell Biol. 2012. PMID: 23091069 Free PMC article.

2

AP-1 differentially expressed proteins Krp1 and fibronectin cooperatively enhance Rho-ROCK-independent mesenchymal invasion by altering the function, localization, and activity of nondifferentially expressed proteins.

Spence HJ, McGarry L, Chew CS, Carragher NO, Scott-Carragher LA, Yuan Z, Croft DR, Olson MF, Frame M, Ozanne BW. Spence HJ, et al. Mol Cell Biol. 2006 Feb;26(4):1480-95. doi: 10.1128/MCB.26.4.1480-1495.2006. Mol Cell Biol. 2006. PMID: 16449658 Free PMC article.

3

Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments.

Caswell PT, Spence HJ, Parsons M, White DP, Clark K, Cheng KW, Mills GB, Humphries MJ, Messent AJ, Anderson KI, McCaffrey MW, Ozanne BW, Norman JC. Caswell PT, et al. Dev Cell. 2007 Oct;13(4):496-510. doi: 10.1016/j.devcel.2007.08.012. Dev Cell. 2007. PMID: 17925226 Free article.

4

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion.

Li A, Dawson JC, Forero-Vargas M, Spence HJ, Yu X, König I, Anderson K, Machesky LM. Li A, et al. Curr Biol. 2010 Feb 23;20(4):339-45. doi: 10.1016/j.cub.2009.12.035. Epub 2010 Feb 4. Curr Biol. 2010. PMID: 20137952 Free PMC article.

5

Functional analysis of Dictyostelium IBARa reveals a conserved role of the I-BAR domain in endocytosis.

Veltman DM, Auciello G, Spence HJ, Machesky LM, Rappoport JZ, Insall RH. Veltman DM, et al. Among authors: spence hj. Biochem J. 2011 May 15;436(1):45-52. doi: 10.1042/BJ20101684. Biochem J. 2011. PMID: 21401524

6

The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migration.

Zech T, Calaminus SD, Caswell P, Spence HJ, Carnell M, Insall RH, Norman J, Machesky LM. Zech T, et al. Among authors: spence hj. J Cell Sci. 2011 Nov 15;124(Pt 22):3753-9. doi: 10.1242/jcs.080986. Epub 2011 Nov 23. J Cell Sci. 2011. PMID: 22114305 Free PMC article.

7

Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1.

Dawson JC, Bruche S, Spence HJ, Braga VM, Machesky LM. Dawson JC, et al. PLoS One. 2012;7(3):e31141. doi: 10.1371/journal.pone.0031141. Epub 2012 Mar 27. PLoS One. 2012. PMID: 22479308 Free PMC article.

8

Scar/WAVE3 contributes to motility and plasticity of lamellipodial dynamics but not invasion in three dimensions.

Spence HJ, Timpson P, Tang HR, Insall RH, Machesky LM. Spence HJ, et al. Biochem J. 2012 Nov 15;448(1):35-42. doi: 10.1042/BJ20112206. Biochem J. 2012. PMID: 22909346 Free PMC article.

9

Loss of Scar/WAVE complex promotes N-WASP- and FAK-dependent invasion.

Tang H, Li A, Bi J, Veltman DM, Zech T, Spence HJ, Yu X, Timpson P, Insall RH, Frame MC, Machesky LM. Tang H, et al. Among authors: spence hj. Curr Biol. 2013 Jan 21;23(2):107-17. doi: 10.1016/j.cub.2012.11.059. Epub 2012 Dec 27. Curr Biol. 2013. PMID: 23273897 Free article.

10

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.

Tyrrell BJ, Woodham EF, Spence HJ, Strathdee D, Insall RH, Machesky LM. Tyrrell BJ, et al. Among authors: spence hj. Pigment Cell Melanoma Res. 2016 Sep;29(5):559-71. doi: 10.1111/pcmr.12506. Pigment Cell Melanoma Res. 2016. PMID: 27390154 Free PMC article.

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