Finke PE - Search Results

1

A comparison of alpha 1-proteinase inhibitor methoxysuccinyl-Ala-Ala-Pro-Val-chloromethylketone and specific beta-lactam inhibitors in an acute model of human polymorphonuclear leukocyte elastase-induced lung hemorrhage in the hamster.

Fletcher DS, Osinga DG, Hand KM, Dellea PS, Ashe BM, Mumford RA, Davies P, Hagmann W, Finke PE, Doherty JB, et al. Fletcher DS, et al. Among authors: finke pe. Am Rev Respir Dis. 1990 Mar;141(3):672-7. doi: 10.1164/ajrccm/141.3.672. Am Rev Respir Dis. 1990. PMID: 2310097

2

Formation of polymorphonuclear leukocyte elastase: alpha 1 proteinase inhibitor complex and A alpha (1-21) fibrinopeptide in human blood stimulated with the calcium ionophore A23187. A model to characterize inhibitors of polymorphonuclear leukocyte elastase.

Pacholok SG, Davies P, Dorn C, Finke P, Hanlon WA, Mumford RA, Humes JL. Pacholok SG, et al. Biochem Pharmacol. 1995 May 17;49(10):1513-20. doi: 10.1016/0006-2952(95)00031-t. Biochem Pharmacol. 1995. PMID: 7763294

3

Orally active beta-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones.

Shah SK, Dorn CP Jr, Finke PE, Hale JJ, Hagmann WK, Brause KA, Chandler GO, Kissinger AL, Ashe BM, Weston H, et al. Shah SK, et al. Among authors: finke pe. J Med Chem. 1992 Oct 16;35(21):3745-54. doi: 10.1021/jm00099a003. J Med Chem. 1992. PMID: 1433189

4

Inhibition of human leukocyte elastase. 3. Synthesis and activity of 3'-substituted cephalosporins.

Shah SK, Brause KA, Chandler GO, Finke PE, Ashe BM, Weston H, Knight WB, Maycock AL, Doherty JB. Shah SK, et al. Among authors: finke pe. J Med Chem. 1990 Sep;33(9):2529-35. doi: 10.1021/jm00171a030. J Med Chem. 1990. PMID: 2391693

5

Orally active beta-lactam inhibitors of human leukocyte elastase. 3. Stereospecific synthesis and structure-activity relationships for 3,3-dialkylazetidin-2-ones.

Finke PE, Shah SK, Fletcher DS, Ashe BM, Brause KA, Chandler GO, Dellea PS, Hand KM, Maycock AL, Osinga DG, et al. Finke PE, et al. J Med Chem. 1995 Jun 23;38(13):2449-62. doi: 10.1021/jm00013a021. J Med Chem. 1995. PMID: 7608910

6

An inhibitor of leukocyte elastase prevents immune complex-mediated hemorrhage in the rat lung.

Fletcher DS, Osinga DG, Keenan K, Bonney RJ, Doherty JB, Finke PE, Shah SK, Davies P. Fletcher DS, et al. Among authors: finke pe. J Pharmacol Exp Ther. 1995 Jul;274(1):548-54. J Pharmacol Exp Ther. 1995. PMID: 7616444

7

Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase.

Doherty JB, Shah SK, Finke PE, Dorn CP Jr, Hagmann WK, Hale JJ, Kissinger AL, Thompson KR, Brause K, Chandler GO, et al. Doherty JB, et al. Among authors: finke pe. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8727-31. doi: 10.1073/pnas.90.18.8727. Proc Natl Acad Sci U S A. 1993. PMID: 8378355 Free PMC article.

8

Orally active beta-lactam inhibitors of human leukocyte elastase. 2. Effect of C-4 substitution.

Hagmann WK, Kissinger AL, Shah SK, Finke PE, Dorn CP, Brause KA, Ashe BM, Weston H, Maycock AL, Knight WB, et al. Hagmann WK, et al. Among authors: finke pe. J Med Chem. 1993 Mar 19;36(6):771-7. doi: 10.1021/jm00058a015. J Med Chem. 1993. PMID: 8459404

9

PMN elastases: a comparison of the specificity of human isozymes and the enzyme from other species toward substrates and inhibitors.

Green BG, Weston H, Ashe BM, Doherty J, Finke P, Hagmann W, Lark M, Mao J, Maycock A, Moore V, et al. Green BG, et al. Arch Biochem Biophys. 1991 Apr;286(1):284-92. doi: 10.1016/0003-9861(91)90042-h. Arch Biochem Biophys. 1991. PMID: 1897955

10

The discovery and biologic properties of cephalosporin-based inhibitors of PMN elastase.

Davies P, Ashe BM, Bonney RJ, Dorn C, Finke P, Fletcher D, Hanlon WA, Humes JL, Maycock A, Mumford RA, et al. Davies P, et al. Ann N Y Acad Sci. 1991;624:219-29. doi: 10.1111/j.1749-6632.1991.tb17021.x. Ann N Y Acad Sci. 1991. PMID: 2064223 Review. No abstract available.

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