Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

42 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response.
Lewis JP, Horenstein RB, Ryan K, O'Connell JR, Gibson Q, Mitchell BD, Tanner K, Chai S, Bliden KP, Tantry US, Peer CJ, Figg WD, Spencer SD, Pacanowski MA, Gurbel PA, Shuldiner AR. Lewis JP, et al. Among authors: horenstein rb. Pharmacogenet Genomics. 2013 Jan;23(1):1-8. doi: 10.1097/FPC.0b013e32835aa8a2. Pharmacogenet Genomics. 2013. PMID: 23111421 Free PMC article.
Paraoxonase 1 (PON1) gene variants are not associated with clopidogrel response.
Lewis JP, Fisch AS, Ryan K, O'Connell JR, Gibson Q, Mitchell BD, Shen H, Tanner K, Horenstein RB, Pakzy R, Tantry US, Bliden KP, Gurbel PA, Shuldiner AR. Lewis JP, et al. Among authors: horenstein rb. Clin Pharmacol Ther. 2011 Oct;90(4):568-74. doi: 10.1038/clpt.2011.194. Epub 2011 Aug 31. Clin Pharmacol Ther. 2011. PMID: 21881565 Free PMC article. Clinical Trial.
The CYP2C19*17 variant is not independently associated with clopidogrel response.
Lewis JP, Stephens SH, Horenstein RB, O'Connell JR, Ryan K, Peer CJ, Figg WD, Spencer SD, Pacanowski MA, Mitchell BD, Shuldiner AR. Lewis JP, et al. Among authors: horenstein rb. J Thromb Haemost. 2013 Sep;11(9):1640-6. doi: 10.1111/jth.12342. J Thromb Haemost. 2013. PMID: 23809542 Free PMC article.
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.
Shuldiner AR, O'Connell JR, Bliden KP, Gandhi A, Ryan K, Horenstein RB, Damcott CM, Pakyz R, Tantry US, Gibson Q, Pollin TI, Post W, Parsa A, Mitchell BD, Faraday N, Herzog W, Gurbel PA. Shuldiner AR, et al. Among authors: horenstein rb. JAMA. 2009 Aug 26;302(8):849-57. doi: 10.1001/jama.2009.1232. JAMA. 2009. PMID: 19706858 Free PMC article.
Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes.
Lewis JP, Ryan K, O'Connell JR, Horenstein RB, Damcott CM, Gibson Q, Pollin TI, Mitchell BD, Beitelshees AL, Pakzy R, Tanner K, Parsa A, Tantry US, Bliden KP, Post WS, Faraday N, Herzog W, Gong Y, Pepine CJ, Johnson JA, Gurbel PA, Shuldiner AR. Lewis JP, et al. Among authors: horenstein rb. Circ Cardiovasc Genet. 2013 Apr;6(2):184-92. doi: 10.1161/CIRCGENETICS.111.964627. Epub 2013 Feb 7. Circ Cardiovasc Genet. 2013. PMID: 23392654 Free PMC article. Clinical Trial.
Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.
Backman JD, O'Connell JR, Tanner K, Peer CJ, Figg WD, Spencer SD, Mitchell BD, Shuldiner AR, Yerges-Armstrong LM, Horenstein RB, Lewis JP. Backman JD, et al. Among authors: horenstein rb. Pharmacogenet Genomics. 2017 Apr;27(4):159-163. doi: 10.1097/FPC.0000000000000272. Pharmacogenet Genomics. 2017. PMID: 28207573 Free PMC article.
42 results