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The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response.
Lewis JP, Horenstein RB, Ryan K, O'Connell JR, Gibson Q, Mitchell BD, Tanner K, Chai S, Bliden KP, Tantry US, Peer CJ, Figg WD, Spencer SD, Pacanowski MA, Gurbel PA, Shuldiner AR. Lewis JP, et al. Among authors: tantry us. Pharmacogenet Genomics. 2013 Jan;23(1):1-8. doi: 10.1097/FPC.0b013e32835aa8a2. Pharmacogenet Genomics. 2013. PMID: 23111421 Free PMC article.
Platelet activation in myocardial ischemic syndromes.
Gurbel PA, Bliden KP, Hayes KM, Tantry U. Gurbel PA, et al. Expert Rev Cardiovasc Ther. 2004 Jul;2(4):535-45. doi: 10.1586/14779072.2.4.535. Expert Rev Cardiovasc Ther. 2004. PMID: 15225113 Review.
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