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Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.
Amambua-Ngwa A, Tetteh KK, Manske M, Gomez-Escobar N, Stewart LB, Deerhake ME, Cheeseman IH, Newbold CI, Holder AA, Knuepfer E, Janha O, Jallow M, Campino S, Macinnis B, Kwiatkowski DP, Conway DJ. Amambua-Ngwa A, et al. Among authors: kwiatkowski dp. PLoS Genet. 2012;8(11):e1002992. doi: 10.1371/journal.pgen.1002992. Epub 2012 Nov 1. PLoS Genet. 2012. PMID: 23133397 Free PMC article.
Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria.
Fry AE, Griffiths MJ, Auburn S, Diakite M, Forton JT, Green A, Richardson A, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Rockett KA, Kwiatkowski DP. Fry AE, et al. Among authors: kwiatkowski dp. Hum Mol Genet. 2008 Feb 15;17(4):567-76. doi: 10.1093/hmg/ddm331. Epub 2007 Nov 13. Hum Mol Genet. 2008. PMID: 18003641 Free PMC article.
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI; Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial; Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Sadaf Farooqi I, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM; KORA; Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Jarvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L; Nurses' Health Study; Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK; Diabetes Genetics Initiative; Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M; SardiNIA Study; Vogel CI, Wallace C, Waterworth DM, Weedon MN; Wellcome Trust Case Control Consortium; Willer CJ; FUSION; Wraig… See abstract for full author list ➔ Loos RJ, et al. Nat Genet. 2008 Jun;40(6):768-75. doi: 10.1038/ng.140. Epub 2008 May 4. Nat Genet. 2008. PMID: 18454148 Free PMC article.
Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Plant D, Gibbons LJ; Wellcome Trust Case Control Consortium; YEAR Consortium; BIRAC Consortium; Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Worthington J. Barton A, et al. Nat Genet. 2008 Oct;40(10):1156-9. doi: 10.1038/ng.218. Epub 2008 Sep 14. Nat Genet. 2008. PMID: 18794857 Free PMC article.
Association of the GNAS locus with severe malaria.
Auburn S, Diakite M, Fry AE, Ghansah A, Campino S, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Koram KA, Oduro AR, Rogers WO, Rockett KA, Haldar K, Kwiatkowski DP. Auburn S, et al. Among authors: kwiatkowski dp. Hum Genet. 2008 Dec;124(5):499-506. doi: 10.1007/s00439-008-0575-8. Epub 2008 Oct 26. Hum Genet. 2008. PMID: 18951142 Free PMC article.
A genetic association study in the Gambia using tagging polymorphisms in the major histocompatibility complex class III region implicates a HLA-B associated transcript 2 polymorphism in severe malaria susceptibility.
Diakite M, Clark TG, Auburn S, Campino S, Fry AE, Green A, Morris AP, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Kwiatkowski DP, Rockett KA. Diakite M, et al. Among authors: kwiatkowski dp. Hum Genet. 2009 Feb;125(1):105-9. doi: 10.1007/s00439-008-0597-2. Epub 2008 Nov 28. Hum Genet. 2009. PMID: 19039607 Free PMC article.
212 results