Toretsky JA - Search Results

1

An intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregation.

Kirilyuk A, Shimoji M, Catania J, Sahu G, Pattabiraman N, Giordano A, Albanese C, Mocchetti I, Toretsky JA, Uversky VN, Avantaggiati ML. Kirilyuk A, et al. Among authors: toretsky ja. PLoS One. 2012;7(11):e48243. doi: 10.1371/journal.pone.0048243. Epub 2012 Nov 1. PLoS One. 2012. PMID: 23133622 Free PMC article.

2

Oncogenic partnerships: EWS-FLI1 protein interactions initiate key pathways of Ewing's sarcoma.

Erkizan HV, Uversky VN, Toretsky JA. Erkizan HV, et al. Among authors: toretsky ja. Clin Cancer Res. 2010 Aug 15;16(16):4077-83. doi: 10.1158/1078-0432.CCR-09-2261. Epub 2010 Jun 14. Clin Cancer Res. 2010. PMID: 20547696 Free PMC article. Review.

3

Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity.

Schlottmann S, Erkizan HV, Barber-Rotenberg JS, Knights C, Cheema A, Uren A, Avantaggiati ML, Toretsky JA. Schlottmann S, et al. Among authors: toretsky ja. Front Oncol. 2012 Sep 7;2:107. doi: 10.3389/fonc.2012.00107. eCollection 2012. Front Oncol. 2012. PMID: 22973553 Free PMC article.

4

YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion.

Rahim S, Beauchamp EM, Kong Y, Brown ML, Toretsky JA, Üren A. Rahim S, et al. Among authors: toretsky ja. PLoS One. 2011 Apr 29;6(4):e19343. doi: 10.1371/journal.pone.0019343. PLoS One. 2011. PMID: 21559405 Free PMC article.

5

Beta-catenin accelerates human papilloma virus type-16 mediated cervical carcinogenesis in transgenic mice.

Bulut G, Fallen S, Beauchamp EM, Drebing LE, Sun J, Berry DL, Kallakury B, Crum CP, Toretsky JA, Schlegel R, Üren A. Bulut G, et al. Among authors: toretsky ja. PLoS One. 2011;6(11):e27243. doi: 10.1371/journal.pone.0027243. Epub 2011 Nov 7. PLoS One. 2011. PMID: 22087269 Free PMC article.

6

Targeting Intrinsically Disordered Transcription Factors: Changing the Paradigm.

Tsafou K, Tiwari PB, Forman-Kay JD, Metallo SJ, Toretsky JA. Tsafou K, et al. Among authors: toretsky ja. J Mol Biol. 2018 Aug 3;430(16):2321-2341. doi: 10.1016/j.jmb.2018.04.008. Epub 2018 Apr 12. J Mol Biol. 2018. PMID: 29655986 Review.

7

PTPL1: a large phosphatase with a split personality.

Abaan OD, Toretsky JA. Abaan OD, et al. Among authors: toretsky ja. Cancer Metastasis Rev. 2008 Jun;27(2):205-14. doi: 10.1007/s10555-008-9114-2. Cancer Metastasis Rev. 2008. PMID: 18265946 Free PMC article. Review.

8

High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition.

Awad O, Yustein JT, Shah P, Gul N, Katuri V, O'Neill A, Kong Y, Brown ML, Toretsky JA, Loeb DM. Awad O, et al. Among authors: toretsky ja. PLoS One. 2010 Nov 11;5(11):e13943. doi: 10.1371/journal.pone.0013943. PLoS One. 2010. PMID: 21085683 Free PMC article.

9

A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model.

Rahim S, Minas T, Hong SH, Justvig S, Çelik H, Kont YS, Han J, Kallarakal AT, Kong Y, Rudek MA, Brown ML, Kallakury B, Toretsky JA, Üren A. Rahim S, et al. Among authors: toretsky ja. PLoS One. 2014 Dec 5;9(12):e114260. doi: 10.1371/journal.pone.0114260. eCollection 2014. PLoS One. 2014. PMID: 25479232 Free PMC article.

10

Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cells.

Sevim H, Çelik H, Düşünceli L, Ceyhan CS, Molotkova A, Nakazawa K, Graham GT, Petro JR, Toretsky JA, Üren A. Sevim H, et al. Among authors: toretsky ja. PLoS One. 2021 Jun 16;16(6):e0253170. doi: 10.1371/journal.pone.0253170. eCollection 2021. PLoS One. 2021. PMID: 34133426 Free PMC article.

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