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DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.
Schoofs T, Rohde C, Hebestreit K, Klein HU, Göllner S, Schulze I, Lerdrup M, Dietrich N, Agrawal-Singh S, Witten A, Stoll M, Lengfelder E, Hofmann WK, Schlenke P, Büchner T, Hansen K, Berdel WE, Rosenbauer F, Dugas M, Müller-Tidow C. Schoofs T, et al. Among authors: hofmann wk. Blood. 2013 Jan 3;121(1):178-87. doi: 10.1182/blood-2012-08-448860. Epub 2012 Nov 14. Blood. 2013. PMID: 23152544 Free article.
Inhibitory effect of imatinib on normal progenitor cells in vitro.
Bartolovic K, Balabanov S, Hartmann U, Komor M, Boehmler AM, Bühring HJ, Möhle R, Hoelzer D, Kanz L, Hofmann WK, Brümmendorf TH. Bartolovic K, et al. Among authors: hofmann wk. Blood. 2004 Jan 15;103(2):523-9. doi: 10.1182/blood-2003-05-1535. Epub 2003 Sep 11. Blood. 2004. PMID: 12969987 Free article.
Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia: results of a randomized phase 3 trial.
Brune M, Castaigne S, Catalano J, Gehlsen K, Ho AD, Hofmann WK, Hogge DE, Nilsson B, Or R, Romero AI, Rowe JM, Simonsson B, Spearing R, Stadtmauer EA, Szer J, Wallhult E, Hellstrand K. Brune M, et al. Among authors: hofmann wk. Blood. 2006 Jul 1;108(1):88-96. doi: 10.1182/blood-2005-10-4073. Epub 2006 Mar 23. Blood. 2006. PMID: 16556892 Free article. Clinical Trial.
SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations.
Nowak D, Ogawa S, Müschen M, Kato M, Kawamata N, Meixel A, Nowak V, Kim HS, Kang S, Paquette R, Chang MS, Thoennissen NH, Mossner M, Hofmann WK, Kohlmann A, Weiss T, Haferlach T, Haferlach C, Koeffler HP. Nowak D, et al. Among authors: hofmann wk. Blood. 2010 Feb 4;115(5):1049-53. doi: 10.1182/blood-2009-03-210377. Epub 2009 Dec 2. Blood. 2010. PMID: 19965645 Free PMC article.
Detection of differential mitotic cell age in bone marrow CD34(+) cells from patients with myelodysplastic syndrome and acute leukemia by analysis of an epigenetic molecular clock DNA signature.
Mossner M, Hopfer O, Nowak D, Baldus CD, Neumann U, Kmetsch A, Benlasfer O, John T, Perka C, Thiel E, Hofmann WK. Mossner M, et al. Among authors: hofmann wk. Exp Hematol. 2010 Aug;38(8):661-5. doi: 10.1016/j.exphem.2010.03.022. Epub 2010 Jun 16. Exp Hematol. 2010. PMID: 20399247
395 results