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DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.
Schoofs T, Rohde C, Hebestreit K, Klein HU, Göllner S, Schulze I, Lerdrup M, Dietrich N, Agrawal-Singh S, Witten A, Stoll M, Lengfelder E, Hofmann WK, Schlenke P, Büchner T, Hansen K, Berdel WE, Rosenbauer F, Dugas M, Müller-Tidow C. Schoofs T, et al. Among authors: lengfelder e. Blood. 2013 Jan 3;121(1):178-87. doi: 10.1182/blood-2012-08-448860. Epub 2012 Nov 14. Blood. 2013. PMID: 23152544 Free article.
Outcome of elderly patients with acute promyelocytic leukemia: results of the German Acute Myeloid Leukemia Cooperative Group.
Lengfelder E, Hanfstein B, Haferlach C, Braess J, Krug U, Spiekermann K, Haferlach T, Kreuzer KA, Serve H, Horst HA, Schnittger S, Aul C, Schultheis B, Erben P, Schneider S, Müller-Tidow C, Wörmann B, Berdel WE, Sauerland C, Heinecke A, Hehlmann R, Hofmann WK, Hiddemann W, Büchner T; German Acute Myeloid Leukemia Cooperative Group (AMLCG). Lengfelder E, et al. Ann Hematol. 2013 Jan;92(1):41-52. doi: 10.1007/s00277-012-1597-9. Epub 2012 Oct 23. Ann Hematol. 2013. PMID: 23090499 Free PMC article.
In acute promyelocytic leukemia (APL) low BAALC gene expression identifies a patient group with favorable overall survival and improved relapse free survival.
Nolte F, Hecht A, Reinwald M, Nowak D, Nowak V, Hanfstein B, Faldum A, Büchner T, Spiekermann K, Sauerland C, Hofmann WK, Lengfelder E. Nolte F, et al. Among authors: lengfelder e. Leuk Res. 2013 Apr;37(4):378-82. doi: 10.1016/j.leukres.2012.11.018. Epub 2012 Dec 31. Leuk Res. 2013. PMID: 23287429
Acute myeloid leukemia: treatment over 60.
Büchner T, Hiddemann W, Berdel W, Wörmann B, Schoch C, Löffler H, Haferlach T, Schumacher A, Staib P, Balleisen L, Grüneisen A, Rasche H, Aul C, Heyll A, Lengfelder E, Ludwig WD, Maschmeyer G, Eimermacher H, Karow J, Frickhofen N, Hirschmann WD, Sauerland MC; German AML Co-Operative Group. Büchner T, et al. Among authors: lengfelder e. Rev Clin Exp Hematol. 2002 Mar;6(1):46-59; discussion 86-7. doi: 10.1046/j.1468-0734.2002.00059.x. Rev Clin Exp Hematol. 2002. PMID: 12060483 Review.
Treatment concepts of acute promyelocytic leukemia.
Lengfelder E, Saussele S, Weisser A, Büchner T, Hehlmann R. Lengfelder E, et al. Crit Rev Oncol Hematol. 2005 Nov;56(2):261-74. doi: 10.1016/j.critrevonc.2004.08.009. Epub 2005 Oct 19. Crit Rev Oncol Hematol. 2005. PMID: 16236522 Review.
156 results