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Page 1
Inhibition of WISE preserves renal allograft function.
Qian X, Yuan X, Vonderfecht S, Ge X, Lee J, Jurisch A, Zhang L, You A, Fitzpatrick VD, Williams A, Valente EG, Pretorius J, Stevens JL, Tipton B, Winters AG, Graham K, Harriss L, Baker DM, Damore M, Salimi-Moosavi H, Gao Y, Elkhal A, Paszty C, Simonet WS, Richards WG, Tullius SG. Qian X, et al. Among authors: vonderfecht s. J Am Soc Nephrol. 2013 Jan;24(1):66-76. doi: 10.1681/ASN.2012010012. Epub 2012 Nov 26. J Am Soc Nephrol. 2013. PMID: 23184054 Free PMC article.
Long-term inhibition of the glucagon receptor with a monoclonal antibody in mice causes sustained improvement in glycemic control, with reversible alpha-cell hyperplasia and hyperglucagonemia.
Gu W, Yan H, Winters KA, Komorowski R, Vonderfecht S, Atangan L, Sivits G, Hill D, Yang J, Bi V, Shen Y, Hu S, Boone T, Lindberg RA, Véniant MM. Gu W, et al. Among authors: vonderfecht s. J Pharmacol Exp Ther. 2009 Dec;331(3):871-81. doi: 10.1124/jpet.109.157685. Epub 2009 Aug 31. J Pharmacol Exp Ther. 2009. PMID: 19720878
FGF21 promotes metabolic homeostasis via white adipose and leptin in mice.
Véniant MM, Hale C, Helmering J, Chen MM, Stanislaus S, Busby J, Vonderfecht S, Xu J, Lloyd DJ. Véniant MM, et al. Among authors: vonderfecht s. PLoS One. 2012;7(7):e40164. doi: 10.1371/journal.pone.0040164. Epub 2012 Jul 6. PLoS One. 2012. PMID: 22792234 Free PMC article.
A novel statistical algorithm for gene expression analysis helps differentiate pregnane X receptor-dependent and independent mechanisms of toxicity.
Mongan MA, Dunn RT, Vonderfecht S, Everds N, Chen G, Su C, Higgins-Garn M, Chen Y, Afshari CA, Williamson TL, Carlock L, Dipalma C, Moss S, Bussiere J, Qualls C, He YD, Hamadeh HK. Mongan MA, et al. Among authors: vonderfecht s. PLoS One. 2010 Dec 21;5(12):e15595. doi: 10.1371/journal.pone.0015595. PLoS One. 2010. PMID: 21203578 Free PMC article.
RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies.
Stolina M, Schett G, Dwyer D, Vonderfecht S, Middleton S, Duryea D, Pacheco E, Van G, Bolon B, Feige U, Zack D, Kostenuik P. Stolina M, et al. Among authors: vonderfecht s. Arthritis Res Ther. 2009;11(6):R187. doi: 10.1186/ar2879. Epub 2009 Dec 11. Arthritis Res Ther. 2009. PMID: 20003323 Free PMC article.
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice.
Xu J, Lloyd DJ, Hale C, Stanislaus S, Chen M, Sivits G, Vonderfecht S, Hecht R, Li YS, Lindberg RA, Chen JL, Jung DY, Zhang Z, Ko HJ, Kim JK, Véniant MM. Xu J, et al. Among authors: vonderfecht s. Diabetes. 2009 Jan;58(1):250-9. doi: 10.2337/db08-0392. Epub 2008 Oct 7. Diabetes. 2009. PMID: 18840786 Free PMC article.
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