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Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.
Mol Pharmacol. 2013 Feb;83(2):429-38. doi: 10.1124/mol.112.082271. Epub 2012 Nov 27.
Mol Pharmacol. 2013.
PMID: 23188715
Free PMC article.
Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration.
Phelan KD, Mock MM, Kretz O, Shwe UT, Kozhemyakin M, Greenfield LJ, Dietrich A, Birnbaumer L, Freichel M, Flockerzi V, Zheng F.
Phelan KD, et al. Among authors: shwe ut.
Mol Pharmacol. 2012 Mar;81(3):384-92. doi: 10.1124/mol.111.075341. Epub 2011 Dec 5.
Mol Pharmacol. 2012.
PMID: 22144671
Free PMC article.
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Critical role of canonical transient receptor potential channel 7 in initiation of seizures.
Phelan KD, Shwe UT, Abramowitz J, Birnbaumer L, Zheng F.
Phelan KD, et al. Among authors: shwe ut.
Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11533-8. doi: 10.1073/pnas.1411442111. Epub 2014 Jul 21.
Proc Natl Acad Sci U S A. 2014.
PMID: 25049394
Free PMC article.
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TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice.
Phelan KD, Shwe UT, Cozart MA, Wu H, Mock MM, Abramowitz J, Birnbaumer L, Zheng F.
Phelan KD, et al. Among authors: shwe ut.
Epilepsia. 2017 Feb;58(2):247-254. doi: 10.1111/epi.13648. Epub 2016 Dec 24.
Epilepsia. 2017.
PMID: 28012173
Free PMC article.
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Pilocarpine-induced status epilepticus in mice: A comparison of spectral analysis of electroencephalogram and behavioral grading using the Racine scale.
Phelan KD, Shwe UT, Williams DK, Greenfield LJ, Zheng F.
Phelan KD, et al. Among authors: shwe ut.
Epilepsy Res. 2015 Nov;117:90-6. doi: 10.1016/j.eplepsyres.2015.09.008. Epub 2015 Sep 12.
Epilepsy Res. 2015.
PMID: 26432759
Free PMC article.
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Increased Susceptibility to Pilocarpine-Induced Status Epilepticus and Reduced Latency in TRPC1/4 Double Knockout Mice.
Zheng F, Phelan KD, Shwe UT.
Zheng F, et al. Among authors: shwe ut.
Neurol Int. 2023 Dec 6;15(4):1469-1479. doi: 10.3390/neurolint15040095.
Neurol Int. 2023.
PMID: 38132974
Free PMC article.
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Pharmacological Differences between Native Homomeric Transient Receptor Potential Canonical Type 4 Channels and Heteromeric Transient Receptor Potential Canonical Type 1/4 Channels in Lateral Septal Neurons.
Phelan KD, Shwe UT, Zheng F.
Phelan KD, et al. Among authors: shwe ut.
Pharmaceuticals (Basel). 2023 Sep 13;16(9):1291. doi: 10.3390/ph16091291.
Pharmaceuticals (Basel). 2023.
PMID: 37765099
Free PMC article.
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