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A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.
Davies G, Harris SE, Reynolds CA, Payton A, Knight HM, Liewald DC, Lopez LM, Luciano M, Gow AJ, Corley J, Henderson R, Murray C, Pattie A, Fox HC, Redmond P, Lutz MW, Chiba-Falek O, Linnertz C, Saith S, Haggarty P, McNeill G, Ke X, Ollier W, Horan M, Roses AD, Ponting CP, Porteous DJ, Tenesa A, Pickles A, Starr JM, Whalley LJ, Pedersen NL, Pendleton N, Visscher PM, Deary IJ. Davies G, et al. Among authors: knight hm. Mol Psychiatry. 2014 Jan;19(1):76-87. doi: 10.1038/mp.2012.159. Epub 2012 Dec 4. Mol Psychiatry. 2014. PMID: 23207651 Free PMC article.
A common variant in the 3'UTR of the GRIK4 glutamate receptor gene affects transcript abundance and protects against bipolar disorder.
Pickard BS, Knight HM, Hamilton RS, Soares DC, Walker R, Boyd JK, Machell J, Maclean A, McGhee KA, Condie A, Porteous DJ, St Clair D, Davis I, Blackwood DH, Muir WJ. Pickard BS, et al. Among authors: knight hm. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14940-5. doi: 10.1073/pnas.0800643105. Epub 2008 Sep 29. Proc Natl Acad Sci U S A. 2008. PMID: 18824690 Free PMC article.
A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression.
Knight HM, Pickard BS, Maclean A, Malloy MP, Soares DC, McRae AF, Condie A, White A, Hawkins W, McGhee K, van Beck M, MacIntyre DJ, Starr JM, Deary IJ, Visscher PM, Porteous DJ, Cannon RE, St Clair D, Muir WJ, Blackwood DH. Knight HM, et al. Am J Hum Genet. 2009 Dec;85(6):833-46. doi: 10.1016/j.ajhg.2009.11.003. Am J Hum Genet. 2009. PMID: 19944402 Free PMC article.
Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging.
Martinez De La Cruz B, Markus R, Malla S, Haig MI, Gell C, Sang F, Bellows E, Sherif MA, McLean D, Lourdusamy A, Self T, Bodi Z, Smith S, Fay M, Macdonald IA, Fray R, Knight HM. Martinez De La Cruz B, et al. Among authors: knight hm. Mol Psychiatry. 2021 Dec;26(12):7141-7153. doi: 10.1038/s41380-021-01282-z. Epub 2021 Oct 19. Mol Psychiatry. 2021. PMID: 34663904 Free PMC article.
26 results