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A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.
Davies G, Harris SE, Reynolds CA, Payton A, Knight HM, Liewald DC, Lopez LM, Luciano M, Gow AJ, Corley J, Henderson R, Murray C, Pattie A, Fox HC, Redmond P, Lutz MW, Chiba-Falek O, Linnertz C, Saith S, Haggarty P, McNeill G, Ke X, Ollier W, Horan M, Roses AD, Ponting CP, Porteous DJ, Tenesa A, Pickles A, Starr JM, Whalley LJ, Pedersen NL, Pendleton N, Visscher PM, Deary IJ. Davies G, et al. Among authors: whalley lj. Mol Psychiatry. 2014 Jan;19(1):76-87. doi: 10.1038/mp.2012.159. Epub 2012 Dec 4. Mol Psychiatry. 2014. PMID: 23207651 Free PMC article.
Genome-wide association studies establish that human intelligence is highly heritable and polygenic.
Davies G, Tenesa A, Payton A, Yang J, Harris SE, Liewald D, Ke X, Le Hellard S, Christoforou A, Luciano M, McGhee K, Lopez L, Gow AJ, Corley J, Redmond P, Fox HC, Haggarty P, Whalley LJ, McNeill G, Goddard ME, Espeseth T, Lundervold AJ, Reinvang I, Pickles A, Steen VM, Ollier W, Porteous DJ, Horan M, Starr JM, Pendleton N, Visscher PM, Deary IJ. Davies G, et al. Among authors: whalley lj. Mol Psychiatry. 2011 Oct;16(10):996-1005. doi: 10.1038/mp.2011.85. Epub 2011 Aug 9. Mol Psychiatry. 2011. PMID: 21826061 Free PMC article.
Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins.
Hill WD, Davies G, van de Lagemaat LN, Christoforou A, Marioni RE, Fernandes CP, Liewald DC, Croning MD, Payton A, Craig LC, Whalley LJ, Horan M, Ollier W, Hansell NK, Wright MJ, Martin NG, Montgomery GW, Steen VM, Le Hellard S, Espeseth T, Lundervold AJ, Reinvang I, Starr JM, Pendleton N, Grant SG, Bates TC, Deary IJ. Hill WD, et al. Among authors: whalley lj. Transl Psychiatry. 2014 Jan 7;4(1):e341. doi: 10.1038/tp.2013.114. Transl Psychiatry. 2014. PMID: 24399044 Free PMC article.
Cognitive change and the APOE epsilon 4 allele.
Deary IJ, Whiteman MC, Pattie A, Starr JM, Hayward C, Wright AF, Carothers A, Whalley LJ. Deary IJ, et al. Among authors: whalley lj. Nature. 2002 Aug 29;418(6901):932. doi: 10.1038/418932a. Nature. 2002. PMID: 12198535
Searching for genetic influences on normal cognitive ageing.
Deary IJ, Wright AF, Harris SE, Whalley LJ, Starr JM. Deary IJ, et al. Among authors: whalley lj. Trends Cogn Sci. 2004 Apr;8(4):178-84. doi: 10.1016/j.tics.2004.02.008. Trends Cogn Sci. 2004. PMID: 15050514
225 results