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854 results

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Page 1
Lung eQTLs to help reveal the molecular underpinnings of asthma.
Hao K, Bossé Y, Nickle DC, Paré PD, Postma DS, Laviolette M, Sandford A, Hackett TL, Daley D, Hogg JC, Elliott WM, Couture C, Lamontagne M, Brandsma CA, van den Berge M, Koppelman G, Reicin AS, Nicholson DW, Malkov V, Derry JM, Suver C, Tsou JA, Kulkarni A, Zhang C, Vessey R, Opiteck GJ, Curtis SP, Timens W, Sin DD. Hao K, et al. PLoS Genet. 2012;8(11):e1003029. doi: 10.1371/journal.pgen.1003029. Epub 2012 Nov 29. PLoS Genet. 2012. PMID: 23209423 Free PMC article.
Mapping the genetic architecture of gene expression in human liver.
Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R. Schadt EE, et al. Among authors: hao k. PLoS Biol. 2008 May 6;6(5):e107. doi: 10.1371/journal.pbio.0060107. PLoS Biol. 2008. PMID: 18462017 Free PMC article.
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.
Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, Keller MP, Kendziorski CM, Yandell BS, Castro V, Attie AD, Kaplan LM, Schadt EE. Zhong H, et al. Among authors: hao k. PLoS Genet. 2010 May 6;6(5):e1000932. doi: 10.1371/journal.pgen.1000932. PLoS Genet. 2010. PMID: 20463879 Free PMC article.
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver.
Yang X, Zhang B, Molony C, Chudin E, Hao K, Zhu J, Gaedigk A, Suver C, Zhong H, Leeder JS, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich RG, Slatter JG, Schadt EE, Kasarskis A, Lum PY. Yang X, et al. Among authors: hao k. Genome Res. 2010 Aug;20(8):1020-36. doi: 10.1101/gr.103341.109. Epub 2010 Jun 10. Genome Res. 2010. PMID: 20538623 Free PMC article.
Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.
Lamb JR, Zhang C, Xie T, Wang K, Zhang B, Hao K, Chudin E, Fraser HB, Millstein J, Ferguson M, Suver C, Ivanovska I, Scott M, Philippar U, Bansal D, Zhang Z, Burchard J, Smith R, Greenawalt D, Cleary M, Derry J, Loboda A, Watters J, Poon RT, Fan ST, Yeung C, Lee NP, Guinney J, Molony C, Emilsson V, Buser-Doepner C, Zhu J, Friend S, Mao M, Shaw PM, Dai H, Luk JM, Schadt EE. Lamb JR, et al. Among authors: hao k. PLoS One. 2011;6(7):e20090. doi: 10.1371/journal.pone.0020090. Epub 2011 Jul 5. PLoS One. 2011. PMID: 21750698 Free PMC article.
Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.
Thun GA, Imboden M, Ferrarotti I, Kumar A, Obeidat M, Zorzetto M, Haun M, Curjuric I, Couto Alves A, Jackson VE, Albrecht E, Ried JS, Teumer A, Lopez LM, Huffman JE, Enroth S, Bossé Y, Hao K, Timens W, Gyllensten U, Polasek O, Wilson JF, Rudan I, Hayward C, Sandford AJ, Deary IJ, Koch B, Reischl E, Schulz H, Hui J, James AL, Rochat T, Russi EW, Jarvelin MR, Strachan DP, Hall IP, Tobin MD, Dahl M, Fallgaard Nielsen S, Nordestgaard BG, Kronenberg F, Luisetti M, Probst-Hensch NM. Thun GA, et al. Among authors: hao k. PLoS Genet. 2013;9(8):e1003585. doi: 10.1371/journal.pgen.1003585. Epub 2013 Aug 22. PLoS Genet. 2013. PMID: 23990791 Free PMC article.
GSTCD and INTS12 regulation and expression in the human lung.
Obeidat M, Miller S, Probert K, Billington CK, Henry AP, Hodge E, Nelson CP, Stewart CE, Swan C, Wain LV, Soler Artigas M, Melén E, Ushey K, Hao K, Lamontagne M, Bossé Y, Postma DS, Tobin MD, Sayers I, Hall IP. Obeidat M, et al. Among authors: hao k. PLoS One. 2013 Sep 18;8(9):e74630. doi: 10.1371/journal.pone.0074630. eCollection 2013. PLoS One. 2013. PMID: 24058608 Free PMC article.
Lung expression quantitative trait loci data set identifies important functional polymorphisms in the asthma-associated IL1RL1 region.
Akhabir L, Bérubé JC, Bossé Y, Laviolette M, Hao K, Nickle DC, Timens W, Sin DD, Paré PD, Postma DS, Sandford AJ. Akhabir L, et al. Among authors: hao k. J Allergy Clin Immunol. 2014 Sep;134(3):729-31. doi: 10.1016/j.jaci.2014.02.039. Epub 2014 Apr 18. J Allergy Clin Immunol. 2014. PMID: 24746754 No abstract available.
854 results