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The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, MacDonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R. Sebastián C, et al. Among authors: gymrek m. Cell. 2012 Dec 7;151(6):1185-99. doi: 10.1016/j.cell.2012.10.047. Cell. 2012. PMID: 23217706 Free PMC article.
Digital transcriptome profiling from attomole-level RNA samples.
Ozsolak F, Goren A, Gymrek M, Guttman M, Regev A, Bernstein BE, Milos PM. Ozsolak F, et al. Among authors: gymrek m. Genome Res. 2010 Apr;20(4):519-25. doi: 10.1101/gr.102129.109. Epub 2010 Feb 4. Genome Res. 2010. PMID: 20133332 Free PMC article.
EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma.
Riggi N, Knoechel B, Gillespie SM, Rheinbay E, Boulay G, Suvà ML, Rossetti NE, Boonseng WE, Oksuz O, Cook EB, Formey A, Patel A, Gymrek M, Thapar V, Deshpande V, Ting DT, Hornicek FJ, Nielsen GP, Stamenkovic I, Aryee MJ, Bernstein BE, Rivera MN. Riggi N, et al. Among authors: gymrek m. Cancer Cell. 2014 Nov 10;26(5):668-681. doi: 10.1016/j.ccell.2014.10.004. Epub 2014 Oct 30. Cancer Cell. 2014. PMID: 25453903 Free PMC article.
A flexible ChIP-sequencing simulation toolkit.
Zheng A, Lamkin M, Qiu Y, Ren K, Goren A, Gymrek M. Zheng A, et al. Among authors: gymrek m. BMC Bioinformatics. 2021 Apr 20;22(1):201. doi: 10.1186/s12859-021-04097-5. BMC Bioinformatics. 2021. PMID: 33879052 Free PMC article.
Missing heritability may be hiding in repeats.
Gymrek M, Goren A. Gymrek M, et al. Science. 2021 Sep 24;373(6562):1440-1441. doi: 10.1126/science.abl7794. Epub 2021 Sep 23. Science. 2021. PMID: 34554784
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.
Rusu V, Hoch E, Mercader JM, Tenen DE, Gymrek M, Hartigan CR, DeRan M, von Grotthuss M, Fontanillas P, Spooner A, Guzman G, Deik AA, Pierce KA, Dennis C, Clish CB, Carr SA, Wagner BK, Schenone M, Ng MCY, Chen BH; MEDIA Consortium; SIGMA T2D Consortium; Centeno-Cruz F, Zerrweck C, Orozco L, Altshuler DM, Schreiber SL, Florez JC, Jacobs SBR, Lander ES. Rusu V, et al. Among authors: gymrek m. Cell. 2017 Jun 29;170(1):199-212.e20. doi: 10.1016/j.cell.2017.06.011. Cell. 2017. PMID: 28666119 Free PMC article.
The impact of short tandem repeat variation on gene expression.
Fotsing SF, Margoliash J, Wang C, Saini S, Yanicky R, Shleizer-Burko S, Goren A, Gymrek M. Fotsing SF, et al. Among authors: gymrek m. Nat Genet. 2019 Nov;51(11):1652-1659. doi: 10.1038/s41588-019-0521-9. Epub 2019 Nov 1. Nat Genet. 2019. PMID: 31676866 Free PMC article.
The landscape of human STR variation.
Willems T, Gymrek M, Highnam G; 1000 Genomes Project Consortium; Mittelman D, Erlich Y. Willems T, et al. Among authors: gymrek m. Genome Res. 2014 Nov;24(11):1894-904. doi: 10.1101/gr.177774.114. Epub 2014 Aug 18. Genome Res. 2014. PMID: 25135957 Free PMC article.
61 results